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Science is Fun Podcast—Assistant Investigator Seth Shipman describes his remarkable technological advance repurposing CRISPR gene editing technology to record information inside living cells.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
Many changes to the genomes of early humans had opposing effects from each other, possibly because of a delicate balance between improved cognition and psychiatric disease risk
News Release Research (Publication) Data Science and Biotechnology Pollard Lab
Revisit some of Gladstone’s most important stories from the past year
Gladstone Experts Cardiovascular Disease Data Science and Biotechnology Genomic Immunology Neurological Disease Infectious Disease
Katie Pollard is recognized for discovering fast-evolving regions of the human genome and for creating open-source software used by scientists worldwide
Awards News Release Data Science and Biotechnology Pollard Lab Big Data
National Academy of Medicine—Katie Pollard, PhD, senior investigator and director of the Gladstone Institute of Data Science and Biotechnology, has been elected to the National Academy of Medicine, in recognition of her discovery of fast-evolving regions in the human genome associated with psychiatric diseases, and of her open-source software used worldwide by genome scientists.
Gladstone Experts Data Science and Biotechnology Pollard Lab Big Data Genomics Human Genetics Microbiome
Christina Theodoris joins Gladstone as an assistant investigator to find new therapies for people with life-threatening cardiovascular diseases
Institutional News News Release Profile Cardiovascular Disease Data Science and Biotechnology Theodoris Lab
Wired—Measuring which genes are on and which are off in a cell usually requires killing it, meaning any measurement is simply a snapshot in time. Seth Shipman explains how his lab has circumvented this problem by re-engineering parts of a bacterial immune system to create a record of molecular events within a cell.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
Singularity Hub—Genomics tools allow scientists to get a glimpse of what genes are turned on in a cell at one particular moment, but understanding how genes are turned on or off over time, and in what order, has been impossible. Gladstone Investigator Seth Shipman has developed a biological recorder that keeps track of these events, offering a window into how cells change over time.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
Gladstone scientists engineer living biosensors to track the genetic activity of cells
News Release Research (Publication) Data Science and Biotechnology Shipman Lab
The Daily Californian—Senior Investigator Melanie Ott, MD, PhD, and collaborator Abdullah Syed, PhD, a postdoctoral fellow in the laboratory of Senior Investigator Jennifer Doudna, explain how they discovered that antibodies against early versions of the SARS-CoV-2 virus do not protect well against the now widespread and highly contagious Omicron variant, and recommend masking to avoid new infections.
Gladstone Experts COVID-19 Data Science and Biotechnology Infectious Disease Doudna Lab Ott Lab
UCSF News—Nevan Krogan, PhD, a senior investigator at Gladstone and the director of the Quantitative Biosciences Institute at UC San Francisco, leads a vast, international collaborative effort to find drugs against COVID-19 called the QBI Coronavirus Research Group (QCRG). The group recently received $67.5 million from the National Institutes of Health, the largest such award in UCSF's history, to pursue work on coronaviruses and other viruses with pandemic potential.
Gladstone Experts COVID-19 Data Science and Biotechnology Krogan Lab
Catherine Tcheandjieu joins Gladstone Institutes to uncover what predisposes people from diverse ancestries to disease
Institutional News News Release Profile Cardiovascular Disease Data Science and Biotechnology Tcheandjieu Lab
A new catalog to help better understand how HIV hijacks human cells
Research (Publication) HIV/AIDS Data Science and Biotechnology Genomic Immunology Infectious Disease Krogan Lab Marson Lab
The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Infectious Disease Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab
San Jose Mercury News—Senior Investigators Melanie Ott, MD, PhD, and Bruce Conklin, MD, recount how they used miniature balls of beating heart cells called organoids to study the effects of COVID-19 on the heart. The heart cells were derived from a person's skin cells, thanks to technology pioneered by Senior Investigator and Nobel Laureate Shinya Yamanaka, MD, PhD.
Gladstone Experts Stem Cell Core COVID-19 Cardiovascular Disease Data Science and Biotechnology Infectious Disease Conklin Lab Ott Lab Yamanaka Lab Organoids
