Gladstone maintains an active and diverse intellectual property portfolio around technologies, novel approaches to treating disease, and specific therapies.
Several options for licensing Gladstone IP are available to both new start-ups, established companies, and research institutions.
Contact the Corporate Liaison and Ventures team for more information on licensing opportunities.
Patents
Additional technologies not listed here may be available for discussion under confidential disclosure agreement. Contact our legal team for licensing inquiries.
| Title | Patent or Publication Number |
|---|---|
| Chemical Reprogramming to Generate Neuronal Cells | US Patent Publication No. US 2019/0010451 |
| Methods of Treating Disease by Metabolic Control of T-Cell Differentiation | US Patent Publication No. US 2019/0022142 |
| Generation of Expandable Cardiovascular Progenitor Cells | US Patent Publication No. US 2019/0017029 |
| Methods and Compositions for Treating Obesity and/or Diabetes and for Identifying Candidate Treatment Agents | US Patent Publication No. US 2019/0106394 |
| Compositions and Methods for Reactivating Latent Immunodeficiency Virus | US Patent Publication No. US 2018/0002699 |
| Methods for Modulating Genome Editing | US Patent Publication No. US 2018/0016601 |
| Reversion of Primed Pluripotent Stem Cells to Naive Pluripotent Stem Cells | US Patent Publication No. US 2018/0142206 |
| Methods and Compositions for Producing Pancreatic Beta Cells | US Patent Publication No. US 2018/0216076 |
| Methods for Treating a Cytomegalovirus Infection | US Patent Publication No. US 2017/0360778 |
| In Vitro Methods of Differentiating Stem Cells into Neurons and Neurons Generated Using the Same | International Publication No. WO 2017/210138 |
| Methods for Inducing Cardiomyogenesis | US Patent Publication No. US 2016/0194608 |
| Detection of Genome Editing | US Patent Publication No. US 2016/0208319 |
| Small Molecule Cellular Reprogramming to Generate Neuronal Cells | US Patent Publication No. US 2016/0250260 |
| Automated Robotic Microscopy Systems | US Patent Publication No. US 2015/0278625 |
| Compositions, Systems, and Methods for Gene Expression Noise Drug Screening and Uses Thereof | US Patent No. 10,184,933 |
| Compositions and Methods of Use Thereof for Identifying Anti-Viral Agents | US Patent No. 10,106,817 |
| Dual-Color HIV Reporter System for the Detection of Latently Infected Cells | US Patent No. 10,106,818 |
| Substituted Benzoxazine and Related Compounds | US Patent No. 10,087,151 and US Patent Publication No. US 2019/0000817 |
| Compositions and Methods for Treating Dengue Virus Infection | US Patent No. 10,004,751 |
| Generating Definitive Endoderm and Pancreatic Progenitor Cells | US Patent No. 9,909,104 |
| Generating Hepatocytes | US Patent Nos. 9,512,406 and 10,227,565 |
| Methods of Modulating Smooth Muscle Cell Proliferation and Differentiation | US Patent Nos. 8,735,568 and 9,364,506 |
| Methods of Promoting CNS Neuronal Repair by Inhibiting LRP-1 | US Patent No. 9,376,481 |
| Compositions and Methods for Regulating Glucose Metabolism | US Patent No. 9,562,072 |
| Methods of Generating Neural Stem Cells | US Patent Nos. 8,815,589 and 9,249,391 |
| Methods for the Reactivation of Latent HIV Using Cytosine Methylation Inhibitors and NF-ΚB Activators | US Patent No. 9,474,788 |
| Compositions and Methods for Treating Neurological Disorders | US Patent No. 9,359,445 |
| Methods of Treating Neurodegenerative Disease | US Patent No. 9,101,644 |
| Treatment of HIV-1 Infection and AIDS | US Patent Nos. 9,956,260 and 9,352,010 |
| Methods and Compositions for Reducing Amyloid Beta Levels | US Patent Nos. 8,420,613; 8,691,519; and 9,347,085 |
| Use of SIRT1 Activators or Inhibitors to Modulate an Immune Response | US Patent No. 8,748,464 |
| Methods of Modulating Lipid Concentrations in Eukaryotic Cells | US Patent No. 8,435,790 |
| Method for Identifying Agents Capable of Inhibiting APOBEC3C Activity in HIV-Infected Cells | US Patent No. 8,133,666 |
| Small Molecule Inhibitors of Kynurenine-3-Monooxygenase | US Patent Nos. 8,071,631; 7,994,338; and 8,466,182 |
| Method of Increasing Cathepsin B-Induced Cleavage of Amyloid-Β Peptides | US Patent No. 8,388,953 |
| Inhibitors of Kynurenine-3-Monooxygenase | US Patent No. 8,710,237 |
| Methods and Compositions for the Synergistic Activation of Latent HIV | US Patent No. 8,247,613 |
| Methods of Treating Smooth Muscle Cell Disorders | US Patent No. 8,114,853 |
| Diacylglycerol O-Acyltransferase 2α (DGAT2α) | US Patent No. 7,862,819 |
| Methods for Treating Lentivirus Infections | US Patent Nos. 7,723,021 and 8,338,180 |
| Methods and Compositions for Reducing Amyloid Beta Levels | US Patent No. 7,951,367 |
| Immunogenic Compositions Comprising HIV-1 Acetylated Tat Polypeptides | US Patent No. 7,482,016 |
| Methods of Detecting Neurological Disorders | US Patent No. 7,297,836 |
| Acyl CoA: Cholesterol Acyltransferase (ACAT-2) | US Patent Nos. 6,579,974; 6,869,937; and 7,238,779 |
| Robotic Microscopy Systems | US Patent No. 7,139,415 |
| Histone Deacetylase and Methods of Use Thereof | US Patent No. 7,488,587 |
| Virion-Based Fusion Assay | US Patent No. 7,250,251 |
| Mouse Model of Chronic Heart Failure and Coronary Atherosclerosis Regression | US Patent No. 7,960,606 |