Gladstone in the News
September 8, 2023
Alzforum—Loss of synapses in the brain is associated with progression of Alzheimer’s disease. However, a new study led by Lennart Mucke, director of the Gladstone Institute of Neurological Disease, shows that in mice, a mutation associated with increased risk of Alzheimer’s disease results in an excess of synapses. In conjunction with recent work from a few other groups, this suggests that removal of synapses may actually play a protective role against Alzheimer’s, at least early in the disease process.
Gladstone Experts
Alzheimer’s Disease
Neurological Disease
Mucke Lab