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This Is Gladstone.

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Gladstone Institutes is an independent, nonprofit research organization driving a new era of discovery in disease-oriented science—an era in which it’s possible to contemplate cures, not just treatments.

Our mission is to drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment

Papers published in 2025 in scientific journals

Most highly cited researchers in the world in 2025

Patents

Start-ups founded on Gladstone-licensed technology since 2015

Raised by Gladstone-backed start-ups from public and private financing

In commercially sponsored research in the last 5 years

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Gladstone is located in San Francisco, surrounded by three world-class universities and at the epicenter of a thriving biotech and venture capital ecosystem. Our streamlined leadership structure and unique culture allow us to pursue the boldest scientific ideas as urgently as we can, to ultimately help as many patients as possible.

Our Academic Partners

Gladstone is an administratively and financially independent nonprofit organization that enjoys a vibrant partnership with UC San Francisco, one of the nation’s premier health sciences institutions. Most of Gladstone’s principal investigators hold faculty positions at UCSF. Gladstone also has affiliations with UC Berkeley and Stanford University.

Driving a new era of discovery in disease-oriented science

Our Core Values

At Gladstone, the fundamental values of excellence, integrity, rigor, and respect are of the utmost importance, as they are in most great organizations. However, what makes Gladstone special is the set of core values that are perfectly aligned to our culture and guide our decisions.

Our Research Areas

At Gladstone, we leverage cutting-edge technologies and data science to solve the most challenging biomedical problems. Our ultimate goal is to make a substantive impact on medicine and healthcare through our research. By combining the world’s top researchers in AI, stem cells, and gene editing with disease experts, we are driving toward a new class of curative and preventive therapies to overcome disease.

History

Gladstone Institutes was established in 1979 through a generous donation from J. David Gladstone, who left his estate to support medical students interested in research. The trustees in charge of J. David Gladstone’s estate made some bold decisions to turn the original vision into something much larger that would have a huge global impact.

Our People

We encourage experts from different backgrounds to jointly tackle large problems and develop technologies needed to support our mission. We accelerate the pursuit of science by leveraging complementary scientific skills and exemplary administrative expertise. Above all at Gladstone, we champion highly interactive, creative, and innovative approaches to science as we seek prevention, treatments, and cures for major diseases.

Finances

*2025 operating budget

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Contact us

Gladstone Institutes
1650 Owns Street
San Francisco, CA 94158

4157342000

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