Six Gladstone Scientists Named Among World’s Most Highly Cited Researchers

Six scientists from Gladstone Institutes have been named to the 2025 list of Highly Cited Researchers by Clarivate. The list celebrates researchers from around the world who have demonstrated “significant and broad influence,” as reflected by the quantity of their research in the past decade that ranks in the top 1 percent in citations for their field.

"We celebrate the Highly Cited Researchers 2025 for advancing innovation and inspiring the global research community to tackle society's greatest challenges with creativity and ingenuity,” says Bar Veinstein, president of academia and government at Clarivate, in announcing the annual list. “As research environments become more complex, we are committed to upholding the highest standards of research integrity by continuing to strengthen the foundations of our Highly Cited Researchers program."

Of the world’s population of scientists, those who land on the Highly Cited Researchers list are 1 in 1,000, according to Clarivate. Each researcher on the list has authored multiple “Highly Cited Papers” that rank in the top 1 percent by citations for their field over the past 11 years. The list is then refined using other quantitative metrics and evaluated for evidence of community-wide recognition from an international network of citing authors.

The scientists from Gladstone who are named on the 2025 list are:

Ryan Corces, PhD

Corces studies how genetic and environmental factors can impact the risk of developing neurodegenerative diseases such as Alzheimer’s and Parkinson’s. While genetic mutations modify genes directly, other factors such as previous illnesses, exposure to environmental chemicals, or simply the process of aging can leave lasting imprints on the epigenome—the DNA sequences and proteins that control how genes are expressed. Using computational biology, large-scale genetic screens, and other technologies, Corces probes cells derived from patients with the aim of understanding the many facets of disease risk and developing novel therapeutic interventions. Corces is assistant investigator at Gladstone Institutes and assistant professor of neurology at UC San Francisco.

Jennifer Doudna, PhD

Doudna is a global innovator in gene editing, and was awarded the 2020 Nobel Prize in Chemistry—along with her collaborator Emmanuelle Charpentier—for the development of a precise and versatile method for editing the genome called CRISPR-Cas9. CRISPR has opened the floodgates of possibility for human and non-human applications of gene editing, including for the treatment or cure of sickle cell disease, muscular dystrophy, and HIV. In addition to her scientific achievements, Doudna is a leader in public discussion around the ethical implications of gene editing and an advocate for thoughtful approaches to policies around the technology’s use. Doudna is a senior investigator at Gladstone, a professor at UC Berkeley, and investigator at Howard Hughes Medical Institute. She is also president of the Innovative Genomics Institute at UC Berkeley.

Alex Marson, MD, PhD

Marson and his cross-disciplinary team have expanded our understanding of the genetic circuits that control how the human immune system functions. He has pioneered new gene-editing technologies that offer faster, cheaper, and more precise ways to re-write DNA in immune cells so they can be engineered to treat a wide range of diseases. For example, his group is working to develop cells that can recognize and eliminate cancer, fend off infections such as HIV, and reduce inflammation in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Marson is director of the Gladstone-UCSF Institute of Genomic Immunology and center director of the Parker Institute for Cancer Immunotherapy at Gladstone Institutes. He is also a professor at UCSF and director of the CRISPR Cures for Cancer Initiative—a joint effort between Gladstone, UCSF, and the Innovative Genomics Institute.

Alex Pico, PhD

Pico’s work is focused on developing innovative software tools, data visualization technologies, and other resources that can be used to unlock knowledge across diverse areas of biomedicine, from cancer and neurodegenerative diseases to heart disease and immune disorders. Pico pushes for aggressive open access and transparency, and makes all of his lab’s tools freely open to all. He has published data visualizations and other important findings through WikiPathways and the Pathway Figures found through Optical Character Recognition (PFOCR) portal. These efforts have paid off in many ways, including through tangible new insights into COVID-19, glioblastoma, and head and neck cancer.

Katie Pollard, PhD

Pollard and her team leverage data science and AI to decode how genomes work, evolve, and break in disease. Their analyses of massive sets of genomic and epigenomic data include investigating human genetic variation, understanding what makes humans unique compared with other species, and characterizing the genomic diversity of the human microbiome. An evolutionary focus, coupled with rigorous statistical methods and bioinformatics tool development, gives her lab a unique perspective on human biology and disease. Pollard is director of the Gladstone Institute of Data Science and Biotechnology. She is also a UCSF professor and an investigator at Chan Zuckerberg Biohub San Francisco.

Jimmie Ye, PhD

Ye studies the molecular basis of immune-related diseases and the genetic basis for natural variation in the human immune system​. A specialist of “omics” technologies and algorithm development, he contributed to the detailed profiling of millions of immune cells from healthy individuals and patients with immune-related conditions, such as autoimmunity, cancer, and COVID-19. The resulting data has helped create the largest reference to date of immune cell biology in humans.