Gladstone in the News
March 30, 2022
STAT News—Alexander Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, describes new research from his group showing that the immune response in a mouse model of atopic dermatitis is altered by obesity. This difference rendered first-line therapies ineffective in mice, indicating that treatments for inflammatory disorders may need to be tailored to work in individual patients, depending on their metabolic state.
Gladstone Experts
Genomic Immunology
Marson Lab
Disease Models
Metabolism
Article
January 17, 2017
Anti-cancer drug prevented less weight gain and caused mice to burn more calories thanks to higher levels of metabolism-boosting brown fat.
Ding Lab
Metabolism
Diabetes
November 22, 2015
Scientists have revealed that glucocorticoids, a class of steroid hormones that are commonly prescribed as drugs, enhance muscle endurance and alleviate muscular dystrophy through activation of the gene KLF15.
Haldar Lab
Cardiovascular Disease
Basic Science
Metabolism
June 17, 2013
SAN FRANCISCO, CA—Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called “circadian clock” are complex, and the molecular processes behind it have long eluded scientists.
Akassoglou Lab
Metabolism
March 27, 2012
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered a key protein that regulates insulin resistance—the diminished ability of cells to respond to the action of insulin and which sets the stage for the development of the most common form of diabetes.
Akassoglou Lab
Diabetes
Metabolism
August 17, 2011
SAN FRANCISCO, CA—A scientist at the Gladstone Institutes has discovered how a gene known as SIRT3 contributes to a suite of health problems sweeping across America, offering new insight into how to combat these potentially fatal conditions.
Diabetes
Metabolism
March 14, 2009
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that a key enzyme involved in absorbing fat may also be a key to reducing it.
Metabolism
