News

Gladstone in the News November 3, 2025

Heart-on-a-Chip May Lead to New Treatments for Heart Failure

UC Berkeley Engineering—Researchers from Gladstone, including Gladstone President and Investigator Deepak Srivastava, were part of a team that discovered a way to efficiently deliver therapeutic messenger RNA into heart muscle cells, overcoming a bottleneck in heart-failure therapeutics that could open the door to novel, lifesaving treatments.

Gladstone Experts Heart Failure Cardiovascular Disease Srivastava Lab

Article February 25, 2025

Matters of the Heart: A Conversation with Gladstone’s Benoit Bruneau

Bruneau, director of the Gladstone Institute of Cardiovascular Disease, shares exciting recent advances in heart research and talks about the impact of predictive AI.

Gladstone Experts Heart Failure Cardiovascular Disease Alexanian Lab Bruneau Lab Pollard Lab Theodoris Lab AI

Article October 23, 2024

Gladstone Researchers Discover How Chronic Inflammation Worsens Heart Failure

The new findings have implications for developing immune therapies that target heart disease and chronic conditions in other organs.

News Release Research (Publication) Heart Failure Cardiovascular Disease Alexanian Lab Srivastava Lab

Article September 4, 2024

Gladstone’s Catherine Tcheandjieu Gueliatcha Named an ‘Emerging Leader’ by National Academy of Medicine

Tcheandjieu is one of 10 scholars nationwide selected as an emerging leader who's shaping the future of health and medicine.

Awards News Release Heart Failure Data Science and Biotechnology Tcheandjieu Lab AI Big Data

Article August 2, 2023

“A Molecular Biology Tour de Force:” Pinpointing a Heart-Protective DNA Change

A Q&A with researchers Bruce Conklin and Juan Perez-Bermejo

Research (Publication) Mass Spectrometry Facility Heart Failure Data Science and Biotechnology Conklin Lab Krogan Lab Stem Cells/iPSCs

Article September 1, 2022

Revealing Molecular Switches for Heart Disease

Michael Alexanian joins Gladstone Institutes to discover new targets for treating and reversing heart failure

Institutional News News Release Profile Heart Failure Cardiovascular Disease Alexanian Lab

Article June 23, 2021

Flipping a Molecular Switch for Heart Fibrosis

Gladstone researchers discover how to reverse cardiac scarring—and how this could treat heart failure

News Release Research (Publication) Heart Failure Cardiovascular Disease Alexanian Lab Srivastava Lab CRISPR/Gene Editing

Article December 10, 2020

A Potential Therapy for One of the Leading Causes of Heart Disease

A drug candidate found by Gladstone researchers could help prevent tens of thousands of heart surgeries every year

News Release Research (Publication) Heart Failure Cardiovascular Disease Srivastava Lab Theodoris Lab AI CRISPR/Gene Editing Disease Models Stem Cells/iPSCs

Article August 27, 2020

Cellular Energy Audit Reveals Energy Producers and Consumers

A team at Gladstone Institutes screened the human genome for genes that play a role in making or consuming cellular energy

News Release Research (Publication) Parkinson’s Disease Heart Failure Neurological Disease Nakamura Lab Disease Models Genomics Metabolism

Gladstone in the News June 27, 2020

A ‘Cure for Heart Disease’? A Single Shot Succeeds in Monkeys

The New York Times—Gladstone President Deepak Srivastava, MD, and Senior Investigator Jennifer Doudna, PhD, comment on a recent report of the successful use of novel CRISPR technology to lower cholesterol and triglyceride levels in monkeys.

Gladstone Experts Heart Failure Cardiovascular Disease Data Science and Biotechnology Doudna Lab Srivastava Lab CRISPR/Gene Editing Disease Models

Gladstone in the News April 7, 2020

Tackling Heart Disease

The Stem Cell Podcast—Gladstone President Deepak Srivastava describes his work using human induced pluripotent stem cells to investigate the gene networks that dictate cell fate decisions, and how this research could lead to therapeutics for congenital heart disease and heart failure. He also describes the importance of stem cell research in fighting the COVID-19 pandemic.

Gladstone Experts COVID-19 Heart Failure Congenital Heart Disease Cardiovascular Disease Roddenberry Stem Cell Center Srivastava Lab Stem Cells/iPSCs

Article February 24, 2020

Tackling Heart Disease: It Takes a Team

Gladstone researchers are collaborating to solve cardiovascular diseases using new technologies.

Gladstone Experts Research (Publication) Heart Failure Congenital Heart Disease Cardiovascular Disease Data Science and Biotechnology Infectious Disease Bruneau Lab Conklin Lab Krogan Lab

Gladstone in the News January 14, 2020

Stem Cell Patterning by Automated Design

The Stem Cell Podcast—Gladstone Senior Investigator Todd McDevitt describes his work using stem cells to understand how tissues grow and organize themselves, and how these efforts lay the groundwork for regenerative medicine therapies.

Gladstone Experts Heart Failure Cardiovascular Disease McDevitt Lab Organoids Stem Cells/iPSCs

Article December 13, 2019

$13 Million Grant to Probe the Genome of Heart Cells

Team of six laboratories will combine expertise in heart development and -omics technology to probe genome activity and organization in heart cells.

Grants News Release Heart Failure Bruneau Lab Conklin Lab Krogan Lab Pollard Lab Srivastava Lab

Article July 30, 2019

Regenerating the Heart after Tissue Damage

Gladstone scientists gain important insights into the cellular reprogramming process

News Release Research (Publication) Heart Failure Cardiovascular Disease Pollard Lab Srivastava Lab Big Data Stem Cells/iPSCs