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UC Santa Cruz News—To mark the 25th anniversary of the Genome Browser, one of the most widely used resources for genomics worldwide, this article spotlights Gladstone’s Katie Pollard, who worked on the Browser over the course of its history.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics
Two new tools created at Gladstone Institutes allow scientists to study DNA at single-molecule resolution using fewer cells than previously required, with clear applications for cancer and many other diseases.
News Release Research (Publication) Cancer Data Science and Biotechnology Ramani Lab Genomics Human Genetics
A team of researchers from Gladstone Institutes and UC San Francisco combined high-throughput experiments and machine learning to analyze more than 100,000 sequences in human brain cells.
News Release Research (Publication) Data Science and Biotechnology Pollard Lab AI Big Data Developmental Biology Disease Models Genomics Human Genetics
The American Association for the Advancement of Science (AAAS), one of the world’s largest general scientific societies, has elected Gladstone Senior Investigator Katie Pollard, PhD, into its new class of AAAS Fellows, a lifetime honor within the scientific community.
Awards News Release Data Science and Biotechnology Pollard Lab AI Big Data Genomics Human Genetics Microbiome
Fierce Biotech—A naturally occurring mutation in T cells that leads to lymphoma can be weaponized to make engineered T-cell therapies more effective against cancer, including melanoma, findings from a new study in mice suggest. The study’s co-leads, dermatologist Jaehyuk Choi and scientist Kole Roybal, have launched a new biotech company called Moonlight Bio to take their findings to the clinic.
Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab Genomics
Nature—Cancer cells are the ultimate survivors, riddled with mutations that let them thrive when healthy cells would die. These same mutations can boost the ability of game-changing cell therapies to quash cancer, a study in mice shows. “Natural T-cell function isn’t good enough. We need to explore the extremes of T-cell function,” says Kole Roybal, co-author of the new paper.
Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab Genomics
BioTechniques—Researchers at Gladstone Institutes have mapped the human immune response using next-generation CRISPR technology known as base editing. Using this tool, the team was able to identify specific nucleotides within T cells that influence immune cells’ response to stimuli, creating maps of DNA sequences and protein sites that are involved in human immune responses. The discoveries this project has facilitated could improve existing immunotherapies and reveal new drug targets for autoimmune diseases and cancer.
Research (Publication) Autoimmune Diseases Cancer Genomic Immunology Doudna Lab Marson Lab CRISPR/Gene Editing Genomics
The new study from the Marson Lab represents a major stride for human genetics; findings will accelerate the development of new and better therapies for cancer and autoimmune diseases.
News Release Research (Publication) Autoimmune Diseases Cancer Genomic Immunology Marson Lab Basic Science CRISPR/Gene Editing Genomics Human Genetics
New York Times—A group of studies comparing the human genome to that of 239 other mammalian species has cast light on what makes humans unique. In particular, work from Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, shows that changes to the way DNA folds may have been a part of what allowed humans to evolve large, powerful brains.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics Human Genetics
Popular Science—A new study from Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, indicates that chance structural changes in the human genome were what allowed humans to evolve the larger brains that set us apart from our primate ancestors.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics Human Genetics
National Institutes of Health—Senior Investigator Katie Pollard, PhD, is featured for her work on genome organization during heart development and talks about her career path in a recent highlight of the National Institutes of Health’s 4D Nucleome program.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics
Researchers at the Gladstone-UCSF Institute of Genomic Immunology are learning how to harness the power of the human immune system in new ways
Gladstone Experts Cancer Genomic Immunology Carnevale Lab Doudna Lab Marson Lab Pelka Lab Roybal Lab Tang Lab Ye Lab
National Academy of Medicine—Katie Pollard, PhD, senior investigator and director of the Gladstone Institute of Data Science and Biotechnology, has been elected to the National Academy of Medicine, in recognition of her discovery of fast-evolving regions in the human genome associated with psychiatric diseases, and of her open-source software used worldwide by genome scientists.
Gladstone Experts Data Science and Biotechnology Pollard Lab Big Data Genomics Human Genetics Microbiome
Watch recordings from the Gladstone-UCSF Institute of Genomic Immunology Symposium
Gladstone Experts Genomic Immunology Marson Lab Pelka Lab Genomics
Watch the presentations from the inaugural Gladstone-UCSF Institute of Genomic Immunology Symposium
Genomic Immunology Marson Lab Genomics
