News

Article November 5, 2025

Deepak Srivastava Selected to Deliver American Heart Association’s Distinguished Scientist Lecture

Srivastava will present at the American Heart Association’s Scientific Sessions 2025 in New Orleans; the lectureship is a major recognition of excellence by the association.

News Release Cardiovascular Disease Srivastava Lab Genomics Stem Cells/iPSCs

Video November 3, 2025

Science in Seconds | Researchers Pinpoint Key Gene Behind Heart Defects in Down Syndrome

In this video, Gladstone scientists share how they used stem cells, gene editing, and AI to identify a gene driving heart defects in Down syndrome—and how reducing its levels in mice restored normal heart development, offering hope for future treatments

Gladstone Experts Cardiovascular Disease Data Science and Biotechnology Pollard Lab Srivastava Lab AI Big Data CRISPR/Gene Editing Human Genetics Stem Cells/iPSCs

Article October 22, 2025

Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.

News Release Research (Publication) Congenital Heart Disease Cardiovascular Disease Pollard Lab Srivastava Lab AI CRISPR/Gene Editing Stem Cells/iPSCs

Article October 9, 2025

CIRM Awards $7.5 Million in Discovery Grants to Gladstone Investigators

Two ambitious research projects led by Gladstone investigators are boosted by funds from the California Institute for Regenerative Medicine.

Grants News Release Congenital Heart Disease Cardiovascular Disease Bruneau Lab Conklin Lab CRISPR/Gene Editing Human Genetics Regenerative Medicine

Article October 7, 2025

Bringing Modern Science to Vitamin Biology: Isha Jain Wins NIH Transformative Research Award

Leveraging modern scientific tools and techniques, Jain intends to transform our understanding of the critical roles that vitamins play in health and disease.

Awards News Release Cardiovascular Disease Jain Lab Metabolism

Article February 25, 2025

Matters of the Heart: A Conversation with Gladstone’s Benoit Bruneau

Bruneau, director of the Gladstone Institute of Cardiovascular Disease, shares exciting recent advances in heart research and talks about the impact of predictive AI.

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Gladstone in the News February 22, 2025

This New Drug Mimics The Health Effects of Living at High Altitude

Science Alert—Gladstone Investigator Isha Jain and her colleagues developed a drug that reduces oxygen delivery from blood to tissues and could help prevent brain damage caused by diseases that cause a toxic oxygen buildup.

Jain Lab Cardiovascular Disease

Gladstone in the News November 8, 2024

Heart Defects Affect 40,000 US Babies Every Year—But Cutting Edge AI and Stem Cell Tech Will Save Lives and Even Cure Them in the Womb

New York Post—Top health researchers from the Murdoch Children’s Research Institute in Australia have teamed with those from Gladstone Institutes in San Francisco on a new program to develop cutting-edge technologies to treat the underlying causes of childhood heart disease more effectively.

Institutional News Cardiovascular Disease

Article October 30, 2024

Using Human Stem Cells, Genomics, and AI to Solve Childhood Heart Disease

A new collaboration between Gladstone Institutes and Murdoch Children’s Research Institute to accelerate life-saving therapies for children affected by heart disease.

Institutional News Cardiovascular Disease

Article October 23, 2024

Gladstone Researchers Discover How Chronic Inflammation Worsens Heart Failure

The new findings have implications for developing immune therapies that target heart disease and chronic conditions in other organs.

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Article May 10, 2024

Gladstone’s Deepak Srivastava Honored as Most Admired CEO by San Francisco Business Times

The San Francisco Business Times has named Srivastava as one of the Most Admired CEOs among Bay Area businesses and nonprofits. The cardiologist and stem cell pioneer has served in the top leadership role at Gladstone Institutes since 2018.

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Gladstone in the News March 10, 2024

A.I. Is Learning What It Means to Be Alive

New York Times—Several new artificial intelligence-powered programs are setting their sights on the fundamentals of biology. They are not simply tidying up the information that biologists are collecting. They are making discoveries about how genes work and how cells develop. Gladstone Assistant Investigator Christina Theodoris shares her journey of creating the deep learning model GeneFormer.

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Video February 15, 2024

Bay Area Cardiovascular Science Symposium

Watch the scientific presentations from the 2024 Bay Area Cardiovascular Science Symposium

Cardiovascular Disease

Article February 8, 2024

Heart-to-Heart Connection: Exploratorium and Gladstone Bring a Breakthrough Science Exhibit to Life

At San Francisco’s Exploratorium, visitors sync their heartbeat with living heart cells; the first-of-its-kind exhibit was created through the museum’s long-running partnership with scientists at Gladstone Institutes.

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Article December 8, 2023

A Dynamic Picture of How We Respond to High or Low Oxygen Levels

A new study from Gladstone Institutes sheds light on the molecular workings at play when oxygen exceeds normal levels, with findings that may one day inform the decision to use supplemental oxygen as a medical treatment

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