How do brain cells change with age? How are liver cells impacted when someone takes a new medicine? What happens to lung cells after decades of smoking?

To find the answers—which have direct applications for preventing disease and developing new drugs—scientists typically design experiments with living cells, tweaking their DNA or environment to see what happens. But that process is slow, expensive, and difficult to scale up to capture the true complexity of life.

Now, scientists at Gladstone Institutes are leveraging artificial intelligence (AI) to revolutionize how we can approach these crucial questions about the inner workings of the body.

They are developing novel AI models to predict what goes wrong in disease—and how to fix it.

In this video, hear from Gladstone Investigator Christina Theodoris and Gladstone President Deepak Srivastava as they explain how these models work, and how AI can help solve diseases that, so far, have been untreatable.

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