News

Gladstone in the News October 22, 2025

Overactive HMGN1 May Underlie Heart Defects in Down Syndrome

Genetic Engineering & Biotechnology News—Gladstone President Deepak Srivastava explains how his lab’s discovery could pave the way for treatments that prevent heart malformations in people with Down syndrome.

Gladstone Experts Congenital Heart Disease Cardiovascular Disease Srivastava Lab

Article October 22, 2025

Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.

News Release Research (Publication) Congenital Heart Disease Cardiovascular Disease Pollard Lab Srivastava Lab AI CRISPR/Gene Editing Stem Cells/iPSCs

Gladstone in the News October 21, 2025

Safe Epigenetic Reprogramming Enables Simultaneous Multi-Gene Editing in T Cells for Enhanced CAR-T Therapies

Bioengineer.org—In a stunning leap forward for immunotherapy, a team including Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, has unveiled a groundbreaking epigenetic editing platform that redefines the genetic programming of human T cells.

Gladstone Experts Genomic Immunology Marson Lab

Gladstone in the News October 16, 2025

AmfAR Awards New HIV Cure-Focused Research Grants Totaling $2.4 Million

amfAR—Gladstone Investigator Nadia Roan and her collaborator at Stanford University are among five research teams to receive an amfAR grant for novel HIV cure strategies.

Grants HIV/AIDS Roan Lab

Video October 15, 2025

Science in Seconds | The Thinking Microscope: Research Powered by an AI Brain

In this video, Steve Finkbeiner and Jeremy Linsley showcase Gladstone’s groundbreaking “thinking microscope”—an AI-powered system that can design, conduct, and analyze experiments autonomously to uncover new insights into diseases like Alzheimer’s, Parkinson’s, and ALS.

Gladstone Experts ALS Alzheimer’s Disease Parkinson’s Disease Neurological Disease Finkbeiner Lab AI Big Data

Article October 9, 2025

CIRM Awards $7.5 Million in Discovery Grants to Gladstone Investigators

Two ambitious research projects led by Gladstone investigators are boosted by funds from the California Institute for Regenerative Medicine.

Grants News Release Congenital Heart Disease Cardiovascular Disease Bruneau Lab Conklin Lab CRISPR/Gene Editing Human Genetics Regenerative Medicine

Video October 8, 2025

Visualizing Stem Cell Technology: An Animated Explainer

In this animated short, Deepak Srivastava explains how scientists can reprogram ordinary skin or blood cells back in time—turning them into induced pluripotent stem cells which are capable of becoming any cell type in the body.

Gladstone Experts Stem Cells/iPSCs

Article October 7, 2025

Bringing Modern Science to Vitamin Biology: Isha Jain Wins NIH Transformative Research Award

Leveraging modern scientific tools and techniques, Jain intends to transform our understanding of the critical roles that vitamins play in health and disease.

Awards News Release Cardiovascular Disease Jain Lab Metabolism

Gladstone in the News October 7, 2025

CRISPR T-Cells: Programming the Future of Medicine with Alexander Marson

CRISPr T-Cell Therapy: A New Frontier—In this podcast episode, Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, talks about CAR T-cell therapy, using CRISPR to edit T-cells, biotech, and his collaboration with Napster Co-Founder Sean Parker.

Gladstone Experts Genomic Immunology Marson Lab CRISPR/Gene Editing

Gladstone in the News October 6, 2025

Nobel Prize in Physiology or Medicine Is Awarded for Work on Immune Systems

The New York Times—After scientists were awarded the 2025 Nobel Prize in Physiology or Medicine for their discoveries of peripheral immune tolerance, Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, comments on how their work has been central to understanding autoimmune diseases and cancers. (Subscription required.)

Gladstone Experts Autoimmune Diseases Cancer Genomic Immunology Marson Lab

Article October 6, 2025

Katerina Akassoglou Receives Zenith Fellows Award to Advance Alzheimer’s Research

Akassoglou has opened doors to understanding how the blood protein fibrin is involved in Alzheimer’s and other neurodegenerative diseases.

Awards News Release Alzheimer’s Disease Center for Neurovascular Brain Immunology Akassoglou Lab

Gladstone in the News September 26, 2025

Broadening the Battle: Fighting Infectious Diseases Beyond Just Viruses

Bioengineer.org—The Gladstone Institute of Virology has undergone a significant transformation in both name and scientific mission, emerging as the Gladstone Infectious Disease Institute. This change, led by Melanie Ott, director of the newly named institute, signals an ambitious commitment to tackle the complex landscape of infectious diseases that threaten human populations worldwide.

Institutional News Infectious Disease Ott Lab

Gladstone in the News September 26, 2025

New Treatment Shows Promise for Huntington’s Disease

The New York Times—Steve Finkbeiner, director of the Center for Systems and Therapeutics at Gladstone, notes that a new gene therapy shows promise for patients affected by Huntington’s disease, but untreated brain regions may still experience neurodegeneration. (Subscription required.)

Gladstone Experts Huntington’s Disease Neurological Disease Center for Systems and Therapeutics Finkbeiner Lab

Article September 25, 2025

Beyond Viruses: Expanding the Fight Against Infectious Diseases

The newly renamed Gladstone Infectious Disease Institute broadens its mission to address global health threats ranging from antibiotic resistance to infections that cause chronic diseases.

Institutional News News Release Cancer COVID-19 Hepatitis C HIV/AIDS Zika Virus Infectious Disease

Gladstone in the News September 22, 2025

Real-Time Molecular Recorders Expose the Inner Lives of Cells

Nature—Gladstone Investigator Seth Shipman weighs in on the promise of DNA-based “molecular recorders” to reveal how cells develop and change in real time.

Gladstone Experts Shipman Lab CRISPR/Gene Editing