News

Gladstone in the News July 19, 2024

San Francisco Scientists Using AI in Hopes to Better Treat Cancer

ABC7 News—Gladstone's president Deepak Srivastava, and Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, explain how scientists are using artificial intelligence to pinpoint the best ways to treat cancer.

Gladstone Experts Cancer Data Science and Biotechnology Pollard Lab Srivastava Lab AI

Article June 18, 2024

Justin Eyquem Named a 2024 Pew-Stewart Scholar for Cancer Research

Eyquem, an affiliate investigator at Gladstone Institutes, is working to enhance the efficiency of CAR-T therapy, a cancer treatment that modifies T cells to target cancer cells.

Awards News Release Cancer Eyquem Lab

Article June 4, 2024

Scientists Push Single-Molecule DNA Sequencing to the Next Level

Two new tools created at Gladstone Institutes allow scientists to study DNA at single-molecule resolution using fewer cells than previously required, with clear applications for cancer and many other diseases.

News Release Research (Publication) Cancer Data Science and Biotechnology Ramani Lab Genomics Human Genetics

Article May 29, 2024

CRISPR-Based Mapping Uncovers ‘Switches’ for Immune Genes Central to Health

A new study in Nature Genetics expands our understanding of immune regulation and autoimmunity—with findings that could also be used in the development of cancer immunotherapies.

News Release Autoimmune Diseases Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Marson Lab Pollard Lab Ye Lab AI CRISPR/Gene Editing

Article May 24, 2024

Visionary Philanthropists Establish Center to Harness Computational Biology for Cancer Research

A search for the brightest minds in cancer and AI led Hope and Sanjit Biswas to give in their own backyard.

Philanthropy Donor Stories Cancer Biswas Center for Transformative Computational Cancer Biology Data Science and Biotechnology Pollard Lab AI Big Data

Gladstone in the News March 12, 2024

Biswas Family Foundation, Milken Institute Award $14M in Computational Biology Grants

GenomeWeb—The Biswas Family Foundation and the Milken Institute have awarded nearly $14 million in grants to researchers developing artificial intelligence and other computational tools for clinical applications. The money will go to five groups, including one from the Gladstone Institutes that is developing machine-learning models to personalize colorectal and skin cancer diagnosis and treatment.

Grants Cancer Biswas Center for Transformative Computational Cancer Biology Data Science and Biotechnology Pollard Lab AI Big Data

Article March 12, 2024

$5 Million Grant Bets on Computational Biology, AI to Change the Future of Cancer

The Biswas Family Foundation and Milken Institute announce funding to establish a center for computational cancer biology at Gladstone Institutes, led by Senior Investigator Katie Pollard.

Grants News Release Cancer Biswas Center for Transformative Computational Cancer Biology Data Science and Biotechnology Pollard Lab AI Big Data

Article March 1, 2024

Vote for Gladstone in This Year’s ‘STAT Madness’ Tournament

The health and science publication STAT has selected a breakthrough discovery from Gladstone to be part of its annual STAT Madness competition, in which research institutes compete for the title of champion. The winner is deemed the most innovative research institution in the country.

Research (Publication) Cancer Genomic Immunology Doudna Lab CRISPR/Gene Editing

Gladstone in the News February 12, 2024

Using Cancer’s ’Superpower’ to Boost T-cell Therapies in Mice

Fierce Biotech—A naturally occurring mutation in T cells that leads to lymphoma can be weaponized to make engineered T-cell therapies more effective against cancer, including melanoma, findings from a new study in mice suggest. The study’s co-leads, dermatologist Jaehyuk Choi and scientist Kole Roybal, have launched a new biotech company called Moonlight Bio to take their findings to the clinic.

Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab Genomics

Gladstone in the News February 7, 2024

Turbocharged CAR-T Cells Melt Tumours in Mice—Using a Trick from Cancer Cells

Nature—Cancer cells are the ultimate survivors, riddled with mutations that let them thrive when healthy cells would die. These same mutations can boost the ability of game-changing cell therapies to quash cancer, a study in mice shows. “Natural T-cell function isn’t good enough. We need to explore the extremes of T-cell function,” says Kole Roybal, co-author of the new paper.

Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab Genomics

Article February 7, 2024

Scientists Use Cancer’s Strength to Fight Against It

In a new study that appears in Nature, researchers leveraged the power of a naturally occurring mutation in cancerous T cells to create a more powerful immunotherapy

News Release Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab

Gladstone in the News January 16, 2024

Advancing CRISPR Applications: Here, There and Everywhere

BioTechniques—Researchers at Gladstone Institutes have mapped the human immune response using next-generation CRISPR technology known as base editing. Using this tool, the team was able to identify specific nucleotides within T cells that influence immune cells’ response to stimuli, creating maps of DNA sequences and protein sites that are involved in human immune responses. The discoveries this project has facilitated could improve existing immunotherapies and reveal new drug targets for autoimmune diseases and cancer.

Research (Publication) Autoimmune Diseases Cancer Genomic Immunology Doudna Lab Marson Lab CRISPR/Gene Editing Genomics

Article December 13, 2023

Using Next-Gen CRISPR Tool, Gladstone Scientists Create Unprecedented Molecular Map of Human Immune Response

The new study from the Marson Lab represents a major stride for human genetics; findings will accelerate the development of new and better therapies for cancer and autoimmune diseases.

News Release Research (Publication) Autoimmune Diseases Cancer Genomic Immunology Marson Lab Basic Science CRISPR/Gene Editing Genomics Human Genetics

Gladstone in the News November 28, 2023

Cancer Shredder Utilizes CRISPR, Targets Glioblastoma

Genetic Engineering & Biotechnology News—Scientists at the Gladstone Institutes have published a paper in Cell Reports that describes a CRISPR-based technique for treating primary glioblastoma, a common and aggressive form of brain cancer. The paper, titled “Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis,” describes the technique, which the researchers have called “genome shredding.”

Research (Publication) Cancer Genomic Immunology Doudna Lab CRISPR/Gene Editing

Article November 27, 2023

CRISPR-Powered ‘Cancer Shredding’ Technique Opens New Possibility for Treating Most Common and Deadly Brain Cancer

Gladstone Institutes researchers leveraged CRISPR to target and rapidly destroy glioblastoma cells in an approach that could carry over to other highly mutated cancers

News Release Research (Publication) Cancer Doudna Lab CRISPR/Gene Editing