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New study shows reducing levels of the protein tau prevents core autism symptoms in animal models
News Release Research (Publication) Behavioral Core Histology and Light Microscopy Core Alzheimer’s Disease Neurological Disease Mucke Lab
Gladstone started as a single institute in 1979 but has since grown to four institutes which use cutting-edge technology to tackle cardiovascular, neurological, and immunological diseases.
History Cardiovascular Disease Data Science and Biotechnology Neurological Disease Virology Greene Lab Mahley Lab Mucke Lab Pollard Lab Srivastava Lab
Gladstone began as a single entity with a single purpose. But as the scientists followed the science—unencumbered by the red tape of bureaucracy—the purpose, and the focus, grew.
History Institutional News Cardiovascular Disease Data Science and Biotechnology Neurological Disease Virology Finkbeiner Lab Greene Lab Mahley Lab Mucke Lab
As clinical trials in Alzheimer's disease have failed, Gladstone investigators are taking innovative approaches to understanding the disease and finding new therapeutic targets.
Research (Publication) Alzheimer’s Disease Dementia Neurological Disease Huang Lab Mahley Lab Mucke Lab Palop Lab Aging Disease Models
Gladstone scientists uncover new gatekeeper function of anti-aging molecule
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Mucke Lab Aging
Transplanting a special type of neuron into the brain restores cognitive functions in Alzheimer’s models
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Mucke Lab Palop Lab
Gladstone scientists receive funding to develop new drugs to reduce tau levels in the brain
Assay Development and Drug Discovery Core Alzheimer’s Disease Mucke Lab
In a meeting of the minds, Gladstone hosted a national behavioral neuroscience symposium to share scientific breakthroughs and compare research methods.
Behavioral Core Mucke Lab
Gladstone scientists discover how to control the cacophony of electrical activity in the brain, stopping seizures and reducing deficits related to Alzheimer’s disease.
Alzheimer’s Disease Epilepsy Mucke Lab Paz Lab Optogenetics
Scientists at the Gladstone Institutes take a comprehensive approach to dementia research, pursuing several potential causal factors of the disease in the hopes of discovering breakthrough treatments.
Alzheimer’s Disease Gan Lab Huang Lab Mucke Lab
Sumihiro Maeda, a research scientist at Gladstone, shares how his curiosity about where imagination and creativity come from led his path to study Alzheimer's disease.
Mucke Lab
New findings about Alzheimer’s disease advance the search for more effective treatments.
Alzheimer’s Disease Mucke Lab
Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer’s disease.
Mucke Lab Alzheimer’s Disease
Hear Lennart Mucke, MD, Director of the Gladstone Institute of Neurological Disease, discuss progress towards Alzheimer’s cures during his recent City Arts & Lectures appearance.
Mucke Lab Alzheimer’s Disease
Raising levels of the life-extending protein klotho can protect against learning and memory deficits in a mouse model of Alzheimer’s disease, despite the accumulation of Alzheimer-related toxins in the brain.
Mucke Lab Aging Alzheimer’s Disease
