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Science—Building on early discoveries at Gladstone, including in the labs of Lennart Mucke and former investigator Bob Farese Jr., scientists uncovered how loss of the protein progranulin drives frontotemporal dementia—insights that helped launch several therapies now in clinical trials.
Mucke Lab Dementia Alzheimer’s Disease
A team of Gladstone scientists used a new video-based tool to pinpoint otherwise-undetectable signs of early disease.
News Release Research (Publication) Alzheimer’s Disease Dementia Palop Lab AI Disease Models
Gladstone scientists say it’s time to think differently about how to define and treat diseases such as Alzheimer’s and multiple sclerosis.
News Release Research (Publication) Alzheimer’s Disease Dementia Multiple Sclerosis Parkinson’s Disease Neurological Disease Akassoglou Lab
Research from Gladstone Institutes reveals that a blood coagulation protein is responsible for initiating toxic inflammation and neuron loss after a major head injury. The findings can inform new treatment strategies for a condition that often presents long-term health challenges.
News Release Dementia Traumatic Brain Injury Neurological Disease Akassoglou Lab
The 2020 Berkelhammer Scholars break new ground in research on dementias, Parkinson’s disease, and neuropsychiatric disorders
Donor Stories Parkinson’s Disease Alzheimer’s Disease Dementia Neurological Disease Akassoglou Lab Kreitzer Lab Mahley Lab Mucke Lab Nakamura Lab
New study shows how patterns in brain activity can be an early predictor of Alzheimer’s symptoms.
News Release Research (Publication) Behavioral Core Alzheimer’s Disease Dementia Neurological Disease Center for Systems and Therapeutics Huang Lab Stem Cells/iPSCs
As clinical trials in Alzheimer's disease have failed, Gladstone investigators are taking innovative approaches to understanding the disease and finding new therapeutic targets.
Research (Publication) Alzheimer’s Disease Dementia Neurological Disease Huang Lab Mahley Lab Mucke Lab Palop Lab Aging Disease Models
