News

Gladstone in the News August 29, 2022

A Better, Faster, More Effective Way to Edit Genes

Alex Marson, MD, PhD, director of the Gladstone-UCSF Institute of Genomic Immunology, comments on breakthrough technology developed in his lab that will greatly facilitate the large-scale engineering of immune cells for cell-based therapies.

Gladstone Experts Genomic Immunology Marson Lab CRISPR/Gene Editing

Article August 25, 2022

A Cellular Engineering Breakthrough: High-Yield CRISPR Without Viral Vectors

Scientists develop a new approach that produces enough cells for therapeutic applications

News Release Research (Publication) Genomic Immunology Esensten Lab Eyquem Lab Marson Lab CRISPR/Gene Editing

Article August 24, 2022

Giving Immunotherapy Cells Resilience to Pass the “Stress Test”

A Gene Not Previously Known to Regulate Immunity Could Turn Tired T-Cells Around

News Release Research (Publication) Cancer Genomic Immunology Carnevale Lab Marson Lab

Article July 11, 2022

Scientists Map Networks of Disease-Associated Immune Genes

The new immune networks have implications for developing immunotherapies and understanding autoimmune diseases

News Release Research (Publication) Autoimmune Diseases Genomic Immunology Marson Lab

Article June 23, 2022

Scientists Prevent “Exhaustion” in Cancer-Fighting T Cells

The new study paves the way toward more effective cancer immunotherapies

News Release Cancer Genomic Immunology Marson Lab

Gladstone in the News April 6, 2022

Obesity May Alter Inflammation on a Molecular Level, Throwing Current Treatments into Question

Fierce Biotech—Alexander Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, and his colleagues at UC San Francisco and the Salk Institute for Biological Studies, recently showed that obese mice with atopic dermatitis had an altered immune response that made them refractory to anti-inflammatory treatment. Fierce Biotech discusses the implications of this finding for the development of drugs against inflammation and asthma.

Gladstone Experts Genomic Immunology Marson Lab Disease Models

Article April 1, 2022

Researchers Create Functional Map of HIV and T-Cell Interactions

A new catalog to help better understand how HIV hijacks human cells

Research (Publication) HIV/AIDS Data Science and Biotechnology Genomic Immunology Virology Krogan Lab Marson Lab

Gladstone in the News March 30, 2022

Obesity Can Turn a Helpful Immunotherapy into a Harmful One, Mouse Study Shows

STAT News—Alexander Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, describes new research from his group showing that the immune response in a mouse model of atopic dermatitis is altered by obesity. This difference rendered first-line therapies ineffective in mice, indicating that treatments for inflammatory disorders may need to be tailored to work in individual patients, depending on their metabolic state.

Gladstone Experts Genomic Immunology Marson Lab Disease Models Metabolism

Article March 30, 2022

How Obesity Can Rewire the Immune System and the Response to Immunotherapy—and How to Change That

Researchers have discovered why immune treatments for allergies and asthma might not be as effective in obese mice and humans

News Release Research (Publication) Genomic Immunology Marson Lab

Article February 3, 2022

Scientists Reveal “Rosetta Stone” of Immune Cell Function

Researchers adapt a variation of the CRISPR-Cas9 system to activate genes in human immune cells and study the consequences

News Release Research (Publication) Genomic Immunology Marson Lab CRISPR/Gene Editing

Video November 18, 2021

Innovators of Genomic Immunology

Watch recordings from the Gladstone-UCSF Institute of Genomic Immunology Symposium

Gladstone Experts Genomic Immunology Marson Lab Pelka Lab Genomics

Article September 21, 2021

Meet Gladstone: Rosmely Hernandez

Born in Cuba, Rosmely Hernandez explains how her grandfather’s battle with Parkinson’s disease sparked her desire to pursue a career in science

Graduate Students and Postdocs Profile Marson Lab

Article May 28, 2021

Gladstone Scientist Uses YouTube to Fight COVID-19 Misinformation in India

Unable to return to his home country during the COVID-19 surge in India, a Gladstone postdoc took to YouTube to share useful information about the virus and how to stay protected

Gladstone Experts Graduate Students and Postdocs COVID-19 Marson Lab

Article May 11, 2021

Gene Editing Expands to New Types of Immune Cells

Gladstone researchers fine-tuned CRISPR-Cas9 genome editing to work on human immune cells called monocytes

News Release Research (Publication) Data Science and Biotechnology Genomic Immunology Krogan Lab Marson Lab CRISPR/Gene Editing

Article April 21, 2021

XYZeq: A Better Map of Cell Diversity

Researchers developed a new technique that lets them map variation across the cells in a tissue or tumor

News Release Research (Publication) Genomic Immunology Marson Lab Single Cell