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Graduate Student Emily Bulger describes her work in the Bruneau Lab, her family roots in science, and the scientist she'd like to have a conversation with
Profile Bruneau Lab
The new study from the Marson Lab represents a major stride for human genetics; findings will accelerate the development of new and better therapies for cancer and autoimmune diseases.
News Release Research (Publication) Autoimmune Diseases Cancer Genomic Immunology Marson Lab Basic Science CRISPR/Gene Editing Genomics Human Genetics
Nature—Recent work by Gladstone Senior Investigator Yadong Huang and his team on the APOE4 Christchurch mutation is featured in a review of the potential for CRISPR to revert mutations that cause Alzheimer's disease.
Gladstone Experts Alzheimer’s Disease Neurological Disease Huang Lab CRISPR/Gene Editing
Melanie Ott, director of the Gladstone Institute of Virology, reflects on the breakthroughs driven by the COVID-19 pandemic and explains why virologists’ work is never done
Gladstone Experts COVID-19 Infectious Disease Ott Lab
A new study from Gladstone Institutes sheds light on the molecular workings at play when oxygen exceeds normal levels, with findings that may one day inform the decision to use supplemental oxygen as a medical treatment
News Release Research (Publication) Cardiovascular Disease Jain Lab
Genetic Engineering & Biotechnology News—In addition to genetic changes, environmental factors are associated with the development of birth defects. A new study led by Deepak Srivastava, president of Gladstone Institutes, reveals how maternal diabetes alters a small subset of cells in the developing heart in a way that can lead to congenital heart defects.
Gladstone Experts Congenital Heart Disease Diabetes Cardiovascular Disease Srivastava Lab Single Cell
The cutting-edge research methods that led to the discovery could be used to find other connections between environmental factors and birth defects.
News Release Research (Publication) Cardiovascular Disease Srivastava Lab
Genetic Engineering & Biotechnology News—Scientists at the Gladstone Institutes have published a paper in Cell Reports that describes a CRISPR-based technique for treating primary glioblastoma, a common and aggressive form of brain cancer. The paper, titled “Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis,” describes the technique, which the researchers have called “genome shredding.”
Research (Publication) Cancer Genomic Immunology Doudna Lab CRISPR/Gene Editing
Gladstone Institutes researchers leveraged CRISPR to target and rapidly destroy glioblastoma cells in an approach that could carry over to other highly mutated cancers
News Release Research (Publication) Cancer Doudna Lab CRISPR/Gene Editing
Fortune—Researchers are investigating the possibility that people who suffer from Long COVID might be at elevated risk of developing cancer. Melanie Ott, director of the Gladstone Institute of Virology, explains that viruses related to SARS-CoV-2 have been shown to inactivate oncosuppressor proteins, which may predispose patients to cancer.
Gladstone Experts Cancer COVID-19 Infectious Disease Ott Lab
Dorman served as a Gladstone trustee for over 30 years
History Profile
Magdalena Zernicka-Goetz, recipient of the 2023 Ogawa-Yamanaka Stem Cell Prize, has created self-assembling embryo-like models that are advancing regenerative medicine
Awards Ogawa Stem Cell Prize Profile Stem Cells/iPSCs
Research Associate Christina Buselli describes her work in the Finkbeiner lab, her path to science, and the questions she wishes she could ask her grandfather
Profile Finkbeiner Lab
New research sheds light on protective mechanisms of the “Christchurch mutation”
News Release Research (Publication) Alzheimer’s Disease Center for Translational Advancement Neurological Disease Huang Lab
