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Researchers used virus-like particles to identify which mutations of the Omicron SARS-CoV-2 virus make it more effective at infecting cells and escaping antibodies
News Release Research (Publication) COVID-19 Virology Doudna Lab Ott Lab
ABC News—Gladstone virologists investigated the effect of the Omicron variant on the immune response. Melanie Ott describes her team’s discovery that previous infection with Omicron does not result in strong immunity to other known SARS-CoV-2 variants. However, as Nadia Roan explains, individuals who were vaccinated before becoming infected with Omicron did have a broadly protective immune response, emphasizing the importance of the vaccines in saving lives.
Gladstone Experts COVID-19 Virology Doudna Lab Greene Lab Ott Lab Roan Lab
Without vaccination, infection with Omicron fails to confer robust immunity against other COVID-19 variants
News Release Research (Publication) COVID-19 Virology Doudna Lab Ott Lab Roan Lab
NIH Director’s Blog—The Delta variant of SARS-CoV-2 is driving the latest surge of COVID-19 cases in the United States. New research from Senior Investigators Jennifer Doudna and Melanie Ott explains how mutations in this variant increase transmissibility.
Gladstone Experts COVID-19 Virology Doudna Lab Ott Lab
Using virus-like particles, researchers find an unexpected explanation for why some coronavirus variants spread faster
Research (Publication) Data Science and Biotechnology Virology Doudna Lab Ott Lab
San Francisco Business Times—Senior Investigator Melanie Ott, MD, PhD, and Graduate Student Parinaz Fozouni explain how the CRISPR- and smartphone-based diagnostic platform they recently developed with UC Berkeley Dan Fletcher, PhD, and Nobel Laureate Jennifer Doudna, PhD, could allow low-cost and widespread testing and help to quickly curb the course of this and future pandemics.
COVID-19 Virology Doudna Lab Ott Lab CRISPR/Gene Editing
A Gladstone discovery could be selected as the top innovation in biomedicine
Awards COVID-19 Doudna Lab Krogan Lab Ott Lab CRISPR/Gene Editing
Gladstone President Deepak Srivastava moderated a conversation with Jennifer Doudna and Shinya Yamanaka.
Philanthropy Doudna Lab Yamanaka Lab CRISPR/Gene Editing Stem Cells/iPSCs
ABC7 News—Gladstone Institute of Virology Director Melanie Ott, MD, PhD, and Graduate Student Parinaz Fozouni comment on the COVID-19 detection test they recently developed with Nobel Laureate Jennifer Doudna, PhD, and UC Berkeley Professor Dan Fletcher, PhD, using CRISPR and smartphone technology.
Gladstone Experts COVID-19 Virology Doudna Lab Ott Lab CRISPR/Gene Editing
Forbes—In an article about the need for rapid testing to monitor and curb the COVID-19 pandemic, Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology, explains the advantages of the CRISPR- and smartphone-based detection platform she developed with Senior Investigator and Nobel Laureate Jennifer Doudna, PhD, and UC Berkeley Professor Dan Fletcher, PhD.
Gladstone Experts COVID-19 Data Science and Biotechnology Virology Doudna Lab Ott Lab
San Francisco Business Times—Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology, discusses the rapid, smartphone-based Coronavirus detection assay her group recently described in the scientific publication Cell. The assay was developed by Graduate Student Parinaz Fozouni, in collaboration with the labs of Senior Scientist and Nobel Laureate Jennifer Doudna, PhD, and of UC Berkeley Bioengineering Professor Dan Fletcher, PhD.
Gladstone Experts COVID-19 Data Science and Biotechnology Virology Doudna Lab Ott Lab
The rapid, one-step mobile test could help combat the pandemic and fully reopen communities
News Release COVID-19 Data Science and Biotechnology Virology Doudna Lab Ott Lab CRISPR/Gene Editing
Nature—Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology, explains how the CRISPR-based coronavirus test she recently developed with Nobel Laureate and Senior Investigator Jennifer Doudna, PhD, measures up against conventional, PCR-based tests.
Gladstone Experts COVID-19 Virology Doudna Lab Ott Lab CRISPR/Gene Editing
USA Today—Senior Investigator and Nobel Laureate Jennifer Doudna, PhD, shares her view of CRISPR-based coronavirus detection kits and the possibility they might be deployed during the current pandemic. She and Senior Investigator Melanie Ott, MD, PhD, recently described the test they developed together in a publication posted on the electronic preprint platform bioRxiv.
Gladstone Experts COVID-19 Data Science and Biotechnology Virology Doudna Lab Ott Lab CRISPR/Gene Editing
Doudna’s discovery of the CRISPR-Cas9 system revolutionized biomedical research
Awards News Release Data Science and Biotechnology Virology Doudna Lab CRISPR/Gene Editing
