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The Science of Solving Disease

Gladstone is 100% dedicated to disease-focused research. Our biologists, chemists, engineers, and data scientists collaborate deeply to understand how the human body works and what goes wrong in disease. We work with the utmost urgency, knowing every day that patients are waiting for better treatments—and cures.

Alzheimer’s Disease

Alzheimer’s Disease

Gladstone's scientists are pursuing multiple research fronts—from genetics to protein biology to inflammation—in the ongoing effort to understand, detect, and ultimately overcome Alzheimer's disease.

Autoimmune Disease

Autoimmune Disease

Gladstone scientists combine genetics, immunology, and gene editing to uncover how autoimmune diseases develop and discover new therapies for these complex, progressive conditions.

Cancer

Cancer

Gladstone researchers are uncovering the genetic drivers of cancer and developing innovative gene-editing and immunotherapy strategies to improve treatment for hard-to-treat cancers.

Congenital Heart Disease

Congenital Heart Disease

Researchers at Gladstone are working to uncover the genetic and developmental causes of congenital heart disease, with the goal of improving diagnosis and developing future therapies.

COVID-19 and Long COVID

COVID-19 and Long COVID

Gladstone researchers are advancing the understanding of COVID-19 and Long COVID to develop better diagnostics, treatments, and vaccines while preparing for future pandemics.

Drug-Resistant Infections

Drug-Resistant Infections

Gladstone scientists are tackling drug-resistant infections by turning the biology of bacteria and the viruses that attack them into tools for new therapies.

Epilepsy

Epilepsy

Epilepsy causes unpredictable, often treatment-resistant seizures, and Gladstone researchers are working to uncover their root causes to develop more targeted therapies.

Heart Failure

Heart Failure

Scientists at Gladstone are working to better understand the underlying causes of heart failure and develop new therapies to repair damaged hearts.

HIV/AIDS

HIV/AIDS

Gladstone scientists are aggressively pursuing a broad range of research that could finally lead to a cure for HIV, as well as ways to improve the overall health of people with HIV.

Huntington’s Disease

Huntington’s Disease

Huntington's disease is a genetic, progressive brain disorder, and Gladstone scientists are working to understand its causes and develop better treatments.

Parkinson’s Disease

Parkinson’s Disease

Gladstone scientists are uncovering the genetic and cellular roots of Parkinson's disease to open new paths toward treating and eventually curing this condition affecting nearly 1 million Americans.

Traumatic Brain Injury

Traumatic Brain Injury

Gladstone scientists are working to decode the brain's response to traumatic brain injury, distinguishing signals that promote healing from those that cause further harm, in search of new therapeutic opportunities.