News

Gladstone in the News November 20, 2025

Mitochondria May Be the Spark That Ignites Parkinson’s Disease

Earth.com—A study by Gladstone Investigator Ken Nakamura helps answer a long-standing debate about Parkinson’s disease: do the cell’s tiny energy factories fail first and spark the disorder, or do they crumble only after brain cells have already begun to die?

Gladstone Experts Parkinson’s Disease Neurological Disease Nakamura Lab

Gladstone in the News November 18, 2025

Late-Onset Parkinson’s Linked to Mitochondrial Protein CHCHD2

Inside Precision Medicine—A new study by Gladstone Investigator Ken Nakamura has found that a mitochondrial protein, CHCHD2, can drive a sequence of cellular events that lead to the development Parkinson’s disease.

Gladstone Experts Parkinson’s Disease Neurological Disease Nakamura Lab

Article November 14, 2025

Evidence Builds for Disrupted Mitochondria as Cause of Parkinson’s

A new study from Gladstone Institutes strengthens the links between energy breakdown in cells and the onset of Parkinson’s, potentially illuminating new paths for treatment.

News Release Research (Publication) Parkinson’s Disease Neurological Disease Nakamura Lab

Video October 15, 2025

Science in Seconds | The Thinking Microscope: Research Powered by an AI Brain

In this video, Steve Finkbeiner and Jeremy Linsley showcase Gladstone’s groundbreaking “thinking microscope”—an AI-powered system that can design, conduct, and analyze experiments autonomously to uncover new insights into diseases like Alzheimer’s, Parkinson’s, and ALS.

Gladstone Experts ALS Alzheimer’s Disease Parkinson’s Disease Neurological Disease Finkbeiner Lab AI Big Data

Article August 27, 2025

Overworked Brain Cells May Burn Out in Parkinson’s Disease

A discovery about the consequence of neuron overactivity could lead to new methods of treating or preventing Parkinson’s disease.

News Release Research (Publication) Parkinson’s Disease Neurological Disease Nakamura Lab

Gladstone in the News July 28, 2025

Gladstone Institutes Develops AI-Powered Thinking Microscope

ABC7 News—Steve Finkbeiner, director of the Center for Systems and Therapeutics at Gladstone, describes the revolutionary thinking microscope that his team developed to help identify better treatments for diseases like Alzheimer’s, Parkinson’s, and ALS.

Gladstone Experts ALS Alzheimer’s Disease Parkinson’s Disease Center for Systems and Therapeutics Finkbeiner Lab

Article July 21, 2025

Inside the Brain: Tackling Neurological Disease at Its Roots

For World Brain Day, discover some of Gladstone’s latest breakthroughs in neurological research.

Gladstone Experts Research (Publication) Alzheimer’s Disease COVID-19 Parkinson’s Disease Neurological Disease Akassoglou Lab Corces Lab Huang Lab Mucke Lab

Article October 17, 2024

A New Era of Treating Neurological Diseases at the Blood-Brain-Immune Interface

Gladstone scientists say it’s time to think differently about how to define and treat diseases such as Alzheimer’s and multiple sclerosis.

News Release Research (Publication) Alzheimer’s Disease Dementia Multiple Sclerosis Parkinson’s Disease Neurological Disease Akassoglou Lab

Article January 11, 2024

Cellular Clean Energy: Can Mitochondria Make More Energy Without Collateral Damage?

New research from Gladstone may help in the development of new therapies that target the problem of cellular energy failure—a hallmark of Parkinson’s, Alzheimer’s, and aging in general

News Release Research (Publication) Alzheimer’s Disease Parkinson’s Disease Neurological Disease Nakamura Lab CRISPR/Gene Editing

Article April 18, 2023

Sugar Rush: Scientists Discover Key Role of Glucose in Brain Activity

New details on how healthy neurons metabolize glucose have implications for understanding neurodegenerative diseases

News Release Research (Publication) Parkinson’s Disease Alzheimer’s Disease Neurological Disease Nakamura Lab

Article August 6, 2021

Recycling a Cell’s Energy Centers to Ward Off Parkinson’s Disease

Gladstone researchers tracked mitochondria inside brain cells and uncovered a new recycling pathway that may be linked to disease

News Release Research (Publication) Parkinson’s Disease Neurological Disease Nakamura Lab

Article November 24, 2020

In Memory of David Traitel: Visionary Philanthropist and Champion of Parkinson’s Disease Research

Gladstone remembers a loyal partner in its fight against Parkinson’s disease

Donor Stories Parkinson’s Disease

Article October 14, 2020

Young Scientists Committed to Finding Treatments for Neurodegenerative Diseases

The 2020 Berkelhammer Scholars break new ground in research on dementias, Parkinson’s disease, and neuropsychiatric disorders

Donor Stories Parkinson’s Disease Alzheimer’s Disease Dementia Neurological Disease Akassoglou Lab Kreitzer Lab Mahley Lab Mucke Lab Nakamura Lab

Gladstone in the News October 2, 2020

Next Wave of Bay Area Neuroscience Companies: What Are They Doing Now?

San Francisco Business Times—Gabaeron, founded by Gladstone President Emeritus Bob Mahley, MD, PhD, and Therini Bio (formerly Medared), founded upon work by Senior Investigator Katarina Akassoglou, PhD, are among Bay Area biotech companies focusing on neurological diseases that collectively raised more than $3 billion from venture capital firms and the public capital markets in 2020.

Gladstone Experts Parkinson’s Disease Multiple Sclerosis Alzheimer’s Disease Neurological Disease Akassoglou Lab Mahley Lab

Article August 27, 2020

Cellular Energy Audit Reveals Energy Producers and Consumers

A team at Gladstone Institutes screened the human genome for genes that play a role in making or consuming cellular energy

News Release Research (Publication) Parkinson’s Disease Heart Failure Neurological Disease Nakamura Lab Disease Models Genomics Metabolism