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AARP—Lennart Mucke, director of the Gladstone Institute of Neurological Disease, does not think that viruses cause Alzheimer’s disease, but suggests that they may act as environmental triggers that interact with genetic factors to contribute to disease.
Gladstone Experts Alzheimer’s Disease Neurological Disease Mucke Lab
Mucke, director of the Gladstone Institute of Neurological Disease, discusses what’s next for Alzheimer’s research, the role of nonprofit research in developing new therapies, and why he’s more hopeful than ever for a future where neurodegenerative diseases are fully treatable—and even preventable.
Alzheimer’s Disease Neurological Disease Mucke Lab Aging
Alzforum—Loss of synapses in the brain is associated with progression of Alzheimer’s disease. However, a new study led by Lennart Mucke, director of the Gladstone Institute of Neurological Disease, shows that in mice, a mutation associated with increased risk of Alzheimer’s disease results in an excess of synapses. In conjunction with recent work from a few other groups, this suggests that removal of synapses may actually play a protective role against Alzheimer’s, at least early in the disease process.
Gladstone Experts Alzheimer’s Disease Neurological Disease Mucke Lab
Gladstone scientists show that reducing levels of the protein tau soon after birth can prevent these conditions in an experimental model
News Release Research (Publication) Epilepsy Neurological Disease Mucke Lab
Gladstone scientists identified treatments to block subtle epileptic activity and chronic brain inflammation in a mouse model of Alzheimer’s disease
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Mucke Lab
Gladstone scientists help explain how reducing the protein tau can prevent abnormal brain activity associated with Alzheimer’s disease, autism, and epilepsy
News Release Research (Publication) Alzheimer’s Disease Epilepsy Neurological Disease Mucke Lab
Lennart Mucke is recognized for his pioneering discoveries in research on Alzheimer’s disease and related disorders
Awards News Release Neurological Disease Mucke Lab
A research collaboration to target the protein tau with small molecules
Business Development News Release Alzheimer’s Disease Neurological Disease Mucke Lab
Randi Mott was born in New Jersey but grew up in Florida. She has an extensive orchid collection and would like to meet Austrian zoologist Paul Pfurtscheller
Profile Mucke Lab
Gladstone researchers harness unique tools and perspectives to study life-threatening seizures that lack a cure
Gladstone Experts Epilepsy Neurological Disease Center for Neurovascular Brain Immunology Akassoglou Lab Mucke Lab Palop Lab Paz Lab Deep Dive
The 2020 Berkelhammer Scholars break new ground in research on dementias, Parkinson’s disease, and neuropsychiatric disorders
Donor Stories Parkinson’s Disease Alzheimer’s Disease Dementia Neurological Disease Akassoglou Lab Kreitzer Lab Mahley Lab Mucke Lab Nakamura Lab
With an estimated 44 million diagnosed with Alzheimer’s disease worldwide, research is moving quickly to better understand the disease.
Gladstone Experts Alzheimer’s Disease Neurological Disease Mahley Lab Mucke Lab
San Francisco Chronicle—The COVID-19 pandemic has disrupted many industries, including biomedical research. Senior Investigators Warner Greene and Lennart Mucke describe how some labs have shifted the focus of their work to address the current crisis, while others have been forced to put important work on pause.
Research (Publication) COVID-19 Greene Lab Mucke Lab
GEN—Genetic Engineering and Biotechnology News reports on a recent study from the lab of Lennart Mucke that shows how reducing levels of Tau, a protein associated with Alzheimer’s disease, could prevent some symptoms of autism.
Gladstone Experts Mucke Lab
Spectrum—Lowering the levels of a protein called tau, best known for its involvement in Alzheimer’s disease, eases autism-like traits in mice, according to a study from the lab of Lennart Mucke.
Gladstone Experts Mucke Lab
