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New research sheds light on protective mechanisms of the “Christchurch mutation”
News Release Research (Publication) Alzheimer’s Disease Center for Translational Advancement Neurological Disease Huang Lab
Gladstone researchers discovered how the ApoE4 gene variant makes neurons release an inflammatory signaling molecule—and how blocking that release could prevent or treat Alzheimer’s disease
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Huang Lab
How gene editing and stem cells are working in tandem at Gladstone Institutes to change science and medicine
Deep Dive Stem Cells/iPSCs CRISPR/Gene Editing Srivastava Lab Yamanaka Lab Doudna Lab Conklin Lab Marson Lab Huang Lab Ott Lab
Seo Yeon Yoon, a research scientist in the Huang lab, shares her passion for puzzles and why AAPI Heritage Month is important to her.
Research Associates Committee Profile Huang Lab
Gladstone researchers show that ApoE4 from neurons plays a much more critical role in the disease than previously thought
News Release Research (Publication) Alzheimer’s Disease Center for Translational Advancement Neurological Disease Huang Lab
The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab
Gladstone discoveries compete head-to-head with other scientific advancements
Awards COVID-19 Traumatic Brain Injury Alzheimer’s Disease Huang Lab Paz Lab Weinberger Lab Chaturvedi
BioIT World—Despite decades of research, medical therapies for Alzheimer’s disease have so far proven elusive. Senior Investigator Yadong Huang describes how his innovative approach to drug repurposing has identified a promising candidate drug that is now moving toward clinical trials.
Gladstone Experts Alzheimer’s Disease Neurological Disease Huang Lab
Researchers pinpoint an existing drug that reverses signs of Alzheimer’s disease in mice and may prevent the disease in humans
News Release Research (Publication) Alzheimer’s Disease Huang Lab
New Gladstone research points to a mechanism driven by a protein associated with a higher risk of developing the disease
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Huang Lab Single Cell
Why should athletes and sports fans have all the fun in March?
Gladstone Experts Institutional News Huang Lab Srivastava Lab
STAT—Two Gladstone studies have been selected to participate in STAT Madness—a March Madness-style competition for scientific papers. Voting begins March 2, 2020.
Gladstone Experts Huang Lab Srivastava Lab
National Science Foundation—In a recent National Science Foundation funded-study, Senior Investigator Yadong Huang and his team show how patterns in brain activities can predict Alzheimer’s symptoms.
Gladstone Experts Huang Lab
New study shows how patterns in brain activity can be an early predictor of Alzheimer’s symptoms.
News Release Research (Publication) Behavioral Core Alzheimer’s Disease Dementia Center for Systems and Therapeutics Neurological Disease Huang Lab Stem Cells/iPSCs
Since Shinya Yamanaka discovered a method to create human induced pluripotent stem (iPS) cells, Gladstone researchers have built on this technology to create numerous iPS cell lines, coax iPS cells into a myriad of tissue types, use them as a tool to study disease, and even begin creating therapies using these cells.
Research (Publication) Stem Cell Core Huntington’s Disease Alzheimer’s Disease Finkbeiner Lab Huang Lab McDevitt Lab Srivastava Lab Yamanaka Lab CRISPR/Gene Editing
