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The Unusual Genetic Inheritance That Could Change Alzheimer’s Treatment

Gladstone in the News April 16, 2025

The Unusual Genetic Inheritance That Could Change Alzheimer’s Treatment

Nature—In the 1980s, scientists began studying a family that suffered a genetic form of early-onset Alzheimer’s disease. Three decades later, they identified one member of that family who showed remarkable protection against the cognitive decline of Alzheimer’s due to a rare mutation in the ApoE gene. Now, Gladstone Senior Investigator Yadong Huang and others are working to develop therapies that mimic that protective mutation, hoping to treat or even prevent Alzheimer’s disease.

Gladstone Experts Alzheimer’s Disease Huang Lab

Gladstone Presents Inaugural Sobrato Prize in Neuroscience to Yadong Huang, a Pioneer of Alzheimer’s Research

Yadong Huang at a podium
Article September 25, 2024

Gladstone Presents Inaugural Sobrato Prize in Neuroscience to Yadong Huang, a Pioneer of Alzheimer’s Research

The prize will be awarded annually to a Gladstone scientist who has made breakthrough discoveries in brain research; funds will help advance scientific discoveries from the lab to the clinic.

Awards News Release Alzheimer’s Disease Neurological Disease Huang Lab Aging Human Genetics

Three Ways to Strengthen a Collaborative Culture

Gladstone in the News March 9, 2022

Three Ways to Strengthen a Collaborative Culture

The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.

Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab

Unique Repurposing Approach Identifies Potential Alzheimer’s Disease Drug

Gladstone in the News November 16, 2021

Unique Repurposing Approach Identifies Potential Alzheimer’s Disease Drug

BioIT World—Despite decades of research, medical therapies for Alzheimer’s disease have so far proven elusive. Senior Investigator Yadong Huang describes how his innovative approach to drug repurposing has identified a promising candidate drug that is now moving toward clinical trials.

Gladstone Experts Alzheimer’s Disease Neurological Disease Huang Lab

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