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Scientists at Gladstone show the new method could treat the majority of patients with Charcot-Marie-Tooth disease.
News Release Research (Publication) Neurological Disease Conklin Lab CRISPR/Gene Editing
Seth Shipman and his team recently identified seven new retrons from environmental bacteria by sampling soil and water in nature.
Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
CRISPR Medicine News—Gladstone Investigator Bruce Conklin showed how manipulating DNA repair responses in neurons after CRISPR editing can direct outcomes and improve editing efficiency.
Gladstone Experts Neurological Disease Conklin Lab CRISPR/Gene Editing
The striking findings of a new study could influence how gene therapies are designed for many genetic diseases.
News Release Research (Publication) Neurological Disease Conklin Lab Doudna Lab CRISPR/Gene Editing
In this video, Gladstone scientists share how they used stem cells, gene editing, and AI to identify a gene driving heart defects in Down syndrome—and how reducing its levels in mice restored normal heart development, offering hope for future treatments
Gladstone Experts Cardiovascular Disease Data Science and Biotechnology Pollard Lab Srivastava Lab AI Big Data CRISPR/Gene Editing Human Genetics Stem Cells/iPSCs
A powerful scientific platform opens new possibilities for treating cancer, autoimmune diseases, and other conditions in which reprogrammed T cells could provide a benefit to patients.
News Release Research (Publication) Cancer Genomic Immunology Marson Lab CRISPR/Gene Editing
After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.
News Release Research (Publication) Congenital Heart Disease Cardiovascular Disease Pollard Lab Srivastava Lab AI CRISPR/Gene Editing Stem Cells/iPSCs
Two ambitious research projects led by Gladstone investigators are boosted by funds from the California Institute for Regenerative Medicine.
Grants News Release Congenital Heart Disease Cardiovascular Disease Bruneau Lab Conklin Lab CRISPR/Gene Editing Human Genetics Regenerative Medicine
CRISPr T-Cell Therapy: A New Frontier—In this podcast episode, Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, talks about CAR T-cell therapy, using CRISPR to edit T-cells, biotech, and his collaboration with Napster Co-Founder Sean Parker.
Gladstone Experts Genomic Immunology Marson Lab CRISPR/Gene Editing
Nature—Gladstone Investigator Seth Shipman weighs in on the promise of DNA-based “molecular recorders” to reveal how cells develop and change in real time.
Gladstone Experts Shipman Lab CRISPR/Gene Editing
Bruce Conklin and his team at Gladstone are tackling Charcot-Marie-Tooth (CMT) disease, the most common inherited neurological disorders—for which there is currently no cure.
Gladstone Experts Conklin Lab CRISPR/Gene Editing
For National DNA Day, discover how Gladstone scientists are utilizing the power of DNA to deepen our understanding of disease.
Gladstone Experts Genomic Immunology Data Science and Biotechnology Marson Lab Pollard Lab Ramani Lab Shipman Lab Tcheandjieu Lab Big Data CRISPR/Gene Editing
Nature—Bacteria are under constant attack from viruses called bacteriophages, and have evolved complex methods to fight off those invaders. Gladstone Investigator Seth Shipman describes how his group is capitalizing on one of those bacterial defense systems—retrons—to create new molecular biology tools.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
The San Francisco Experience—In a podcast interview, Gladstone President Deepak Srivastava discusses the mission of Gladstone Institutes, and describes how advances in stem cell biology, genome engineering, and artificial intelligence are making it possible to understand the core of diseases and develop new cures.
Gladstone Experts Srivastava Lab AI CRISPR/Gene Editing Stem Cells/iPSCs
The Medicine Maker—In this Q&A, the head of the California Institute for Regenerative Medicine highlights the game-changing scientific contributions of Gladstone’s Shinya Yamanaka and Jennifer Doudna.
Gladstone Experts CRISPR/Gene Editing Stem Cells/iPSCs
