The center focuses on two connected goals: shrinking the hidden pool of HIV that lingers in the body, and strengthening the immune system’s ability to keep that remaining virus in check.
This strategy is grounded in real biology: a small group of people, called “post-treatment controllers,” still carry small amounts of HIV but can keep it under control naturally, without needing HIV medications.
To find a functional cure for HIV, our investigators are pursuing multiple complementary strategies. One approach tries to safely “wake up” hidden HIV so infected cells become visible and can be found and destroyed. Another approach does the opposite: it aims to keep the remaining virus permanently silenced, so it can never reactivate. The center is also developing next-generation mRNA vaccines that produce virus-like particles, designed to trigger a strong, long-lasting immune response against HIV.
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A new discovery reveals how a SARS-CoV-2 protein reprograms immune cells to accelerate viral spread—and points to a new strategy for therapeutic intervention.
The fellowship provides three years of funding for graduate students pursuing groundbreaking immunology research.
Takahashi is recognized for his pioneering work translating iPS cell technology into a clinically approved therapy for Parkinson’s disease.
An unprecedented map of 22 million immune cells provides the functional rulebook for virtual biology and next-generation immunotherapies.
Our people are our most important asset. We offer a wide array of career opportunities both in our administrative offices and in our labs.
Open PositionsDiscoveries don’t stay in our labs. Gladstone facilitates spinout companies to advance promising therapies, shortening the path between scientific discovery and helping real patients.
Learn MoreYour gift to Gladstone will allow our researchers to pursue high-quality science, focus on disease, and train the next generation of scientific thought leaders.
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