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Obesity Can Turn a Helpful Immunotherapy into a Harmful One, Mouse Study Shows

Gladstone in the News March 30, 2022

Obesity Can Turn a Helpful Immunotherapy into a Harmful One, Mouse Study Shows

STAT News—Alexander Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, describes new research from his group showing that the immune response in a mouse model of atopic dermatitis is altered by obesity. This difference rendered first-line therapies ineffective in mice, indicating that treatments for inflammatory disorders may need to be tailored to work in individual patients, depending on their metabolic state.

Gladstone Experts Genomic Immunology Marson Lab Disease Models Metabolism

Do You Need a 4th Dose of a COVID-19 Vaccine? There’s No One-Size-Fits-All Answer

Gladstone in the News March 30, 2022

Do You Need a 4th Dose of a COVID-19 Vaccine? There’s No One-Size-Fits-All Answer

CBC—The FDA recently authorized a fourth dose of the Pfizer-BioNTech COVID-19 vaccine for all individuals over aged 50, and for those 12 and older with immunodeficiencies. Melanie Ott, director of the Gladstone Institute of Virology, explains that whereas a fourth shot may not be urgently necessary for individuals who are young and healthy, she does encourage those eligible to ensure that they get their third shot (first booster).

Gladstone Experts COVID-19 Virology Ott Lab

Virologist Says 2nd COVID Booster Shot for Everyone Could Be Advised in the Fall

Gladstone in the News March 30, 2022

Virologist Says 2nd COVID Booster Shot for Everyone Could Be Advised in the Fall

ABC News—The FDA recently announced that they would authorize a second COVID-19 vaccine booster shot for people 50 and older, and those 12 and older who are immunocompromised. Senior Investigator Warner Greene explains that the second booster can protect people who don’t have vigorous immune systems from infection, and predicts that it may be more broadly recommended for all adults in the months to come.

Gladstone Experts COVID-19 Virology Greene Lab

Highly-Transmissible COVID Subvariant Increasing in CA, but Expert ‘Doubts’ Lockdowns Will Be Needed

Gladstone in the News March 16, 2022

Highly-Transmissible COVID Subvariant Increasing in CA, but Expert ‘Doubts’ Lockdowns Will Be Needed

ABC News—A sub-variant of Omicron known as BA.2 is causing a spike in COVID-19 cases in Europe, and is predicted to become the globally dominant variant in the coming weeks. However, Senior Investigator Warner Greene says that vaccinated and boosted individuals are still well protected against serious illness, and spread of this new variant is unlikely to lead to new lockdowns.

Gladstone Experts COVID-19 Virology Greene Lab

Three Ways to Strengthen a Collaborative Culture

Gladstone in the News March 9, 2022

Three Ways to Strengthen a Collaborative Culture

The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.

Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab

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