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Transplanting human neurons into mouse brains reveals disease-causing interactions between the APOE4 protein and immune cells.
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Huang Lab
The prize will be awarded annually to a Gladstone scientist who has made breakthrough discoveries in brain research; funds will help advance scientific discoveries from the lab to the clinic.
Awards News Release Alzheimer’s Disease Neurological Disease Huang Lab Aging Human Genetics
Misha Zilberter discusses his Alzheimer's disease research, the importance of collaboration in science, and the advice he has for young scientists
Profile Alzheimer’s Disease Neurological Disease Huang Lab
Washington Post—Gladstone Senior Investigator Yadong Huang offers commentary on a new study examining the protective power of the rare “Christchurch” gene variant against Alzheimer’s. (Subscription required)
Alzheimer’s Disease Huang Lab
Nature—Recent work by Gladstone Senior Investigator Yadong Huang and his team on the APOE4 Christchurch mutation is featured in a review of the potential for CRISPR to revert mutations that cause Alzheimer's disease.
Gladstone Experts Alzheimer’s Disease Neurological Disease Huang Lab CRISPR/Gene Editing
New research sheds light on protective mechanisms of the “Christchurch mutation”
News Release Research (Publication) Alzheimer’s Disease Center for Translational Advancement Neurological Disease Huang Lab
Gladstone researchers discovered how the ApoE4 gene variant makes neurons release an inflammatory signaling molecule—and how blocking that release could prevent or treat Alzheimer’s disease
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Huang Lab
How gene editing and stem cells are working in tandem at Gladstone Institutes to change science and medicine
Deep Dive Stem Cells/iPSCs CRISPR/Gene Editing Srivastava Lab Yamanaka Lab Doudna Lab Conklin Lab Marson Lab Huang Lab Ott Lab
Seo Yeon Yoon, a research scientist in the Huang lab, shares her passion for puzzles and why AAPI Heritage Month is important to her.
Research Associates Committee Profile Huang Lab
Gladstone researchers show that ApoE4 from neurons plays a much more critical role in the disease than previously thought
News Release Research (Publication) Alzheimer’s Disease Center for Translational Advancement Neurological Disease Huang Lab
The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab
Gladstone discoveries compete head-to-head with other scientific advancements
Awards COVID-19 Traumatic Brain Injury Alzheimer’s Disease Huang Lab Paz Lab Weinberger Lab Chaturvedi
BioIT World—Despite decades of research, medical therapies for Alzheimer’s disease have so far proven elusive. Senior Investigator Yadong Huang describes how his innovative approach to drug repurposing has identified a promising candidate drug that is now moving toward clinical trials.
Gladstone Experts Alzheimer’s Disease Neurological Disease Huang Lab
Researchers pinpoint an existing drug that reverses signs of Alzheimer’s disease in mice and may prevent the disease in humans
News Release Research (Publication) Alzheimer’s Disease Huang Lab
New Gladstone research points to a mechanism driven by a protein associated with a higher risk of developing the disease
News Release Research (Publication) Alzheimer’s Disease Neurological Disease Huang Lab Single Cell
