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Forward-looking researchers at the Gladstone Institutes are working to solve the stem cell supply problem by pursuing innovative ways to improve stem cell engineering and scale-up tissue manufacturing.
Conklin Lab Ding Lab McDevitt Lab Stem Cells/iPSCs
Gladstone scientists have invented a new way to create micro heart muscle from stem cells using a unique dog bone dish. The three-dimensional tissue is ideal for disease modeling and drug testing.
Conklin Lab Stem Cells/iPSCs
Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have manipulated the genome of induced pluripotent stem cells for the first time using a variation of the CRISPR system.
Conklin Lab CRISPR/Gene Editing Stem Cells/iPSCs
The new system could serve as a drug-screening tool to make pregnancies safer.
Conklin Lab Stem Cells/iPSCs
The discovery of cell reprogramming by Shinya Yamanaka changed the way scientists see cell biology, but the details of how it works are still being defined. In a recent paper, the labs of Yamanaka and Bruce Conklin show how one key factor—NANOG—is involved in the process.
Conklin Lab Yamanaka Lab Stem Cells/iPSCs
Gladstone’s innovative technique in stem cells could boost scientists’ ability to study—and ultimately cure—genetic disease.
Conklin Lab CRISPR/Gene Editing Stem Cells/iPSCs
