Marianne Bronner, PhD
Marianne Bronner has been a principal investigator for over 30 years. The Bronner laboratory uses a multiorganismal approach to study the development and evolution of neural crest cells and ectodermal placodes. The neural crest is a migratory embryonic cell population that forms at the border between the neural plate and the future epidermis. Neural crest cells delaminate from the neuroepithelium in a rostrocaudal wave and migrate throughout the embryo to form a wide range of derivatives. They build much of the head skeleton, forming also all epidermal pigment cells, and together with cranial placodes, the peripheral nervous system. Because these cell types are unique to vertebrates, a comparative approach across vertebrates, from the basal lamprey to zebrafish, frog, chick, and mouse, provides insights into conserved and divergent mechanisms of neural crest and placode development.
Because neural crest-derived cells are involved in a variety of birth defects and cancers such as neurofibromatosis, melanoma, neuroblastoma, the lab's results on the mechanisms underlying neural crest development and evolution provide important clues regarding the mistakes that may lead to abnormal development or loss of the differentiated state.
Hosted by Benoit Bruneau, PhD, director of the Gladstone Institute of Cardiovascular Disease.
DatesNovember 14, 2022
AudienceGladstone and UCSF
The GICD/CVRI Seminar series is a collaborative series between the Gladstone Institute of Cardiovascular Disease and the Cardiovascular Research Institute at UC San Francisco.
Diversity, Equity, and Inclusion
At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.
We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.