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What If Cells Kept Receipts of Their Gene Expression?

Gladstone in the News August 12, 2022

What If Cells Kept Receipts of Their Gene Expression?

Wired—Measuring which genes are on and which are off in a cell usually requires killing it, meaning any measurement is simply a snapshot in time. Seth Shipman explains how his lab has circumvented this problem by re-engineering parts of a bacterial immune system to create a record of molecular events within a cell.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

New DNA ‘Camcorders’ Can Record ‘Movies’ of a Cell’s Development Through Time

Gladstone in the News August 2, 2022

New DNA ‘Camcorders’ Can Record ‘Movies’ of a Cell’s Development Through Time

Singularity Hub—Genomics tools allow scientists to get a glimpse of what genes are turned on in a cell at one particular moment, but understanding how genes are turned on or off over time, and in what order, has been impossible. Gladstone Investigator Seth Shipman has developed a biological recorder that keeps track of these events, offering a window into how cells change over time.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

Gladstone Investigator on 2019 Science News’ List of 10 Young Scientists to Watch

Seth Shipman
Article October 1, 2019

Gladstone Investigator on 2019 Science News’ List of 10 Young Scientists to Watch

Gladstone Assistant Investigator Seth Shipman is on this year’s Science News list of 10 Young Scientists to Watch. Shipman invented a system to store information in the genome of living cells. He is using tools from genetics and synthetic biology to understand fundamental aspects of cell biology and brain circuitry.

Awards Data Science and Biotechnology Shipman Lab

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