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Watch this panel discussion that addresses the impact and hurdles associated with developing a cure for HIV
HIV/AIDS Ott Lab
Nob Hill Gazette—Home to 30 labs and 500 researchers, Gladstone is a hub of cutting-edge research and advances toward cures for the most devastating diseases.
Gladstone Experts Doudna Lab Greene Lab Ott Lab Srivastava Lab Weinberger Lab Yamanaka Lab Big Data CRISPR/Gene Editing Stem Cells/iPSCs
The Daily Californian—Senior Investigator Melanie Ott, MD, PhD, and collaborator Abdullah Syed, PhD, a postdoctoral fellow in the laboratory of Senior Investigator Jennifer Doudna, explain how they discovered that antibodies against early versions of the SARS-CoV-2 virus do not protect well against the now widespread and highly contagious Omicron variant, and recommend masking to avoid new infections.
Gladstone Experts COVID-19 Data Science and Biotechnology Virology Doudna Lab Ott Lab
Researchers used virus-like particles to identify which mutations of the Omicron SARS-CoV-2 virus make it more effective at infecting cells and escaping antibodies
News Release Research (Publication) COVID-19 Virology Doudna Lab Ott Lab
Gladstone researchers find new evidence against using BET inhibitors to treat COVID-19
News Release Research (Publication) COVID-19 Virology Ott Lab
Washington Post—Even as COVID restrictions are easing, case numbers are rising around the country. Melanie Ott, director of the Gladstone Institute of Virology, explains that recent research from her group shows that individuals infected with the Omicron variant have limited natural immunity, and may still be susceptible to infection with Omicron subvariants.
Gladstone Experts COVID-19 Virology Ott Lab
ABC News—Gladstone virologists investigated the effect of the Omicron variant on the immune response. Melanie Ott describes her team’s discovery that previous infection with Omicron does not result in strong immunity to other known SARS-CoV-2 variants. However, as Nadia Roan explains, individuals who were vaccinated before becoming infected with Omicron did have a broadly protective immune response, emphasizing the importance of the vaccines in saving lives.
Gladstone Experts COVID-19 Virology Doudna Lab Greene Lab Ott Lab Roan Lab
USA Today—When the Omicron variant of SARS-CoV-2 swept the country this winter, many had hoped it might help move the population closer to herd immunity. However, Director of the Gladstone Institute of Virology Melanie Ott describes her team’s research that shows that previous infection with Omicron does not provide strong protection against infection with other variants.
Gladstone Experts COVID-19 Virology Ott Lab
Without vaccination, infection with Omicron fails to confer robust immunity against other COVID-19 variants
News Release Research (Publication) COVID-19 Virology Doudna Lab Ott Lab Roan Lab
STAT News—COVID-19 case numbers are rising once again across the United States. Melanie Ott, director of the Gladstone Institute of Virology, explains that the virus is adapting to a new immune landscape, with variants emerging that are able to cause infection even in individuals who were previously infected.
Gladstone Experts COVID-19 Virology Ott Lab
A new platform designed by Gladstone scientists for studying how the immune system responds to hepatitis C virus could speed the hunt for a vaccine
News Release Research (Publication) Hepatitis C Virology McDevitt Lab Ott Lab Organoids
CBC—The FDA recently authorized a fourth dose of the Pfizer-BioNTech COVID-19 vaccine for all individuals over aged 50, and for those 12 and older with immunodeficiencies. Melanie Ott, director of the Gladstone Institute of Virology, explains that whereas a fourth shot may not be urgently necessary for individuals who are young and healthy, she does encourage those eligible to ensure that they get their third shot (first booster).
Gladstone Experts COVID-19 Virology Ott Lab
The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab
San Jose Mercury News—Senior Investigators Melanie Ott, MD, PhD, and Bruce Conklin, MD, recount how they used miniature balls of beating heart cells called organoids to study the effects of COVID-19 on the heart. The heart cells were derived from a person’s skin cells, thanks to technology pioneered by Senior Investigator and Nobel Laureate Shinya Yamanaka, MD, PhD.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Conklin Lab Ott Lab Yamanaka Lab Organoids
Gladstone program managers adapted the format of the PUMAS summer internship to meet the needs and safety of students and mentors
Ott Lab Diversity
