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CRISPR Screening Identifies Human Host Pathways That Facilitate Coronavirus Infection

Gladstone in the News September 26, 2020

CRISPR Screening Identifies Human Host Pathways That Facilitate Coronavirus Infection

Life Science—The online science news hub Life Sciences highlights recent work from Senior Investigators Melanie Ott, MD, PhD, and Nevan Krogan, PhD, and their colleagues at BioHub and Synthego Corporation. The work describes the identification of host factors common to three coronaviruses including SARS-CoV-2, and could help bootstrap efforts to stem current and future coronavirus epidemics.

Gladstone Experts COVID-19 Data Science and Biotechnology Virology Krogan Lab Ott Lab CRISPR/Gene Editing

With Coronavirus Antibodies Fading Fast, Vaccine Hopes Fade Too

Gladstone in the News July 16, 2020

With Coronavirus Antibodies Fading Fast, Vaccine Hopes Fade Too

San Francisco Chronicle—Commenting on the disappointing recent reports about antibodies as barriers against coronavirus infection, Senior Investigator Nevan Krogan, PhD, and Visiting Scientist Danielle Swaney, PhD, emphasize the need for drug treatments as an alternative, and describe how they look for such treatments.

Gladstone Experts COVID-19 Data Science and Biotechnology Krogan Lab

Study Reveals Images of the Coronavirus Forming Tentacles in Cells—but Monstrous Discovery Helps Identify New Treatment

Gladstone in the News June 27, 2020

Study Reveals Images of the Coronavirus Forming Tentacles in Cells—but Monstrous Discovery Helps Identify New Treatment

Milwaukee Journal Sentinel—Senior Investigator Nevan Krogan, PhD, explains his team's latest discovery that drugs belonging to a class known as kinase inhibitors can slow SARS-CoV-2 proliferation in cultured cells more efficiently than the antiviral Remdesivir.

Gladstone Experts COVID-19 Data Science and Biotechnology Krogan Lab

Ingredient in Common Over-the-Counter Cough Medicines Helps Coronavirus Grow, Says Research

Gladstone in the News May 2, 2020

Ingredient in Common Over-the-Counter Cough Medicines Helps Coronavirus Grow, Says Research

MEAWW—Gladstone Investigator Nevan Krogan describes his efforts to identify drugs that affect COVID-19, including the finding that a component of cough syrup may have the undesirable effect of improving viral replication.

Gladstone Experts COVID-19 Data Science and Biotechnology Krogan Lab

Old Drugs May Find a New Purpose: Fighting the Coronavirus

Gladstone in the News April 30, 2020

Old Drugs May Find a New Purpose: Fighting the Coronavirus

New York Times—Gladstone Investigator Nevan Krogan describes his team’s effort to identify drugs that target the human proteins that interact with SARS-CoV-2, and the hope that this effort may lead to effective therapies for COVID-19 that can move rapidly through the testing and approval process.

Gladstone Experts COVID-19 Data Science and Biotechnology Krogan Lab

Scientists Have Discovered Drugs That Block Coronavirus, Paving Way for “a Better Drug Sooner”

Gladstone in the News April 30, 2020

Scientists Have Discovered Drugs That Block Coronavirus, Paving Way for “a Better Drug Sooner”

San Francisco Chronicle—Gladstone Senior Investigator Nevan Krogan explains his team’s efforts to understand how COVID-19 interacts with human cells, and how they are using that information to identify drugs that could be used to fight the virus.

Gladstone Experts COVID-19 Data Science and Biotechnology Krogan Lab

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