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Melanie Ott, director of the Gladstone Institute of Virology, reflects on the breakthroughs driven by the COVID-19 pandemic and explains why virologists’ work is never done
Gladstone Experts COVID-19 Virology Ott Lab
Genetic Engineering & Biotechnology News—In addition to genetic changes, environmental factors are associated with the development of birth defects. A new study led by Deepak Srivastava, president of Gladstone Institutes, reveals how maternal diabetes alters a small subset of cells in the developing heart in a way that can lead to congenital heart defects.
Gladstone Experts Congenital Heart Disease Diabetes Cardiovascular Disease Srivastava Lab Single Cell
Fortune—Researchers are investigating the possibility that people who suffer from Long COVID might be at elevated risk of developing cancer. Melanie Ott, director of the Gladstone Institute of Virology, explains that viruses related to SARS-CoV-2 have been shown to inactivate oncosuppressor proteins, which may predispose patients to cancer.
Gladstone Experts Cancer COVID-19 Virology Ott Lab
AHA with JAHA Podcast—In a roundtable forum, the American Heart Association’s 2023 Distinguished Scientists describe their contributions to stroke and cardiovascular research. Gladstone President Deepak Srivastava discusses the use of human iPS cells in drug discovery and his hopes for the future of science and medicine, including applications of artificial intelligence.
Gladstone Experts Congenital Heart Disease Cardiovascular Disease Srivastava Lab Human Genetics Stem Cells/iPSCs
Innovative Genomics Institute—Gladstone Senior Investigator Jennifer Doudna and Affiliate Investigator Jimmie Ye, along with collaborators at the Parker Institute for Cancer Immunology and Stanford, have discovered a way to increase the safety of CRISPR editing by preventing chromosome loss, a toxic side-effect of the technology in some cells.
Gladstone Experts Cancer Data Science and Biotechnology Parker Institute for Cancer Immunotherapy Doudna Lab Ye Lab CRISPR/Gene Editing
PharmaVoice—PharmaVoice recently assembled its annual list of inspiring leaders in the industry. Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, was named to the list as a cancer care visionary, recognized for both his scientific innovation and his dedication to collaboration and mentoring.
Gladstone Experts Genomic Immunology Marson Lab
UCSF News—Gladstone Senior Investigators Alex Marson and Jennifer Doudna, and President of the UC San Francisco Helen Diller Family Comprehensive Cancer Center Alan Ashworth, will head the newly launched CRISPR Cures for Cancer Initiative, which will fund research at the intersection of genomic technologies and cellular immunotherapies at Gladstone Institutes, UC San Francisco, and the Innovative Genomics Institute at UC Berkeley.
Gladstone Experts Cancer Data Science and Biotechnology Genomic Immunology Doudna Lab Marson Lab CRISPR/Gene Editing Stem Cells/iPSCs
An 8-year-old with CMT meets with Gladstone researchers
Gladstone Experts Conklin Lab
Alzforum—Loss of synapses in the brain is associated with progression of Alzheimer’s disease. However, a new study led by Lennart Mucke, director of the Gladstone Institute of Neurological Disease, shows that in mice, a mutation associated with increased risk of Alzheimer’s disease results in an excess of synapses. In conjunction with recent work from a few other groups, this suggests that removal of synapses may actually play a protective role against Alzheimer’s, at least early in the disease process.
Gladstone Experts Alzheimer’s Disease Neurological Disease Mucke Lab
Nob Hill Gazette—Senior Investigator and Nobel Laureate Jennifer Doudna talks about CRISPR, its current and future clinical uses and their ethical implications, her life in science and a new direction for CRISPR called "The Audacious Project".
Gladstone Experts Data Science and Biotechnology Doudna Lab CRISPR/Gene Editing
CVS Health—Innovation in biomedical science is changing the way scientists think about the future of medicine. Gladstone President Deepak Srivastava describes how advances in genomics, gene editing, and cell programming may lead to new cures for human disease.
Gladstone Experts Congenital Heart Disease Cardiovascular Disease Srivastava Lab CRISPR/Gene Editing Human Genetics
Nature Podcast—Assistant Investigator Christina Theodoris explains how she and her collaborators used artificial intelligence to uncover how genes work together to control cells and tissues, even in situations such as rare diseases where data are in limited supply.
Gladstone Experts Cardiovascular Disease Theodoris Lab AI
The Atlantic—The next generation of COVID vaccines may be directed against just one lineage of the Omicron strain. Melanie Ott, director of the Gladstone Institute of Virology, explains why that could be a smart strategy to elicit a strong immune response.
Gladstone Experts COVID-19 Virology Ott Lab
San Francisco Chronicle—Gladstone Senior Investigator Nadia Roan explains that while prior vaccination or exposure to COVID-19 may confer long-term protection against serious disease, a booster shot with the bivalent vaccine will protect you for a few months against new infection.
Gladstone Experts COVID-19 Virology Roan Lab
New York Times—A group of studies comparing the human genome to that of 239 other mammalian species has cast light on what makes humans unique. In particular, work from Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, shows that changes to the way DNA folds may have been a part of what allowed humans to evolve large, powerful brains.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics Human Genetics
