News

Gladstone in the News August 29, 2022

A Better, Faster, More Effective Way to Edit Genes

Alex Marson, MD, PhD, director of the Gladstone-UCSF Institute of Genomic Immunology, comments on breakthrough technology developed in his lab that will greatly facilitate the large-scale engineering of immune cells for cell-based therapies.

Gladstone Experts Genomic Immunology Marson Lab CRISPR/Gene Editing

Article August 25, 2022

A Cellular Engineering Breakthrough: High-Yield CRISPR Without Viral Vectors

Scientists develop a new approach that produces enough cells for therapeutic applications

News Release Research (Publication) Genomic Immunology Esensten Lab Eyquem Lab Marson Lab CRISPR/Gene Editing

Gladstone in the News August 12, 2022

What If Cells Kept Receipts of Their Gene Expression?

Wired—Measuring which genes are on and which are off in a cell usually requires killing it, meaning any measurement is simply a snapshot in time. Seth Shipman explains how his lab has circumvented this problem by re-engineering parts of a bacterial immune system to create a record of molecular events within a cell.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

Gladstone in the News August 2, 2022

New DNA ‘Camcorders’ Can Record ‘Movies’ of a Cell’s Development Through Time

Singularity Hub—Genomics tools allow scientists to get a glimpse of what genes are turned on in a cell at one particular moment, but understanding how genes are turned on or off over time, and in what order, has been impossible. Gladstone Investigator Seth Shipman has developed a biological recorder that keeps track of these events, offering a window into how cells change over time.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

Article February 3, 2022

Scientists Reveal “Rosetta Stone” of Immune Cell Function

Researchers adapt a variation of the CRISPR-Cas9 system to activate genes in human immune cells and study the consequences

News Release Research (Publication) Genomic Immunology Marson Lab CRISPR/Gene Editing

Article January 5, 2022

Researchers Pioneer New Method to Edit Genes in Human Cells

Retrons could revolutionize gene editing for research and medicine

News Release Research (Publication) Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

Article August 17, 2021

A New Approach to Curing HIV

Armed with a $26.5-million grant, a multi-institution collaboratory will tackle HIV in a new way

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Article June 23, 2021

Flipping a Molecular Switch for Heart Fibrosis

Gladstone researchers discover how to reverse cardiac scarring—and how this could treat heart failure

News Release Research (Publication) Heart Failure Cardiovascular Disease Alexanian Lab Srivastava Lab CRISPR/Gene Editing

Article June 21, 2021

How Do Developing Spinal Cords Choose “Heads” or “Tails”?

A new human organoid developed by Gladstone scientists mimics one of the key steps in early embryonic development

News Release Research (Publication) Cardiovascular Disease McDevitt Lab CRISPR/Gene Editing Stem Cells/iPSCs

Article May 11, 2021

Gene Editing Expands to New Types of Immune Cells

Gladstone researchers fine-tuned CRISPR-Cas9 genome editing to work on human immune cells called monocytes

News Release Research (Publication) Data Science and Biotechnology Genomic Immunology Krogan Lab Marson Lab CRISPR/Gene Editing

Gladstone in the News April 8, 2021

At Home, on Your Phone, Results in Minutes: How COVID Has Changed the Future of Health Tests

San Francisco Business Times—Senior Investigator Melanie Ott, MD, PhD, and Graduate Student Parinaz Fozouni explain how the CRISPR- and smartphone-based diagnostic platform they recently developed with UC Berkeley Dan Fletcher, PhD, and Nobel Laureate Jennifer Doudna, PhD, could allow low-cost and widespread testing and help to quickly curb the course of this and future pandemics.

COVID-19 Virology Doudna Lab Ott Lab CRISPR/Gene Editing

Article February 28, 2021

STAT Madness Is on, and Gladstone Is a Finalist

A Gladstone discovery could be selected as the top innovation in biomedicine

Awards COVID-19 Doudna Lab Krogan Lab Ott Lab CRISPR/Gene Editing

Video January 20, 2021

The Convergence of CRISPR and Human Stem Cells

Gladstone President Deepak Srivastava moderated a conversation with Jennifer Doudna and Shinya Yamanaka.

Philanthropy Doudna Lab Yamanaka Lab CRISPR/Gene Editing Stem Cells/iPSCs

Gladstone in the News January 15, 2021

Bay Area Researchers Develop New Rapid COVID-19 Test That Uses Smartphone Camera

ABC7 News—Gladstone Institute of Virology Director Melanie Ott, MD, PhD, and Graduate Student Parinaz Fozouni comment on the COVID-19 detection test they recently developed with Nobel Laureate Jennifer Doudna, PhD, and UC Berkeley Professor Dan Fletcher, PhD, using CRISPR and smartphone technology.

Gladstone Experts COVID-19 Virology Doudna Lab Ott Lab CRISPR/Gene Editing

Article December 10, 2020

A Potential Therapy for One of the Leading Causes of Heart Disease

A drug candidate found by Gladstone researchers could help prevent tens of thousands of heart surgeries every year

News Release Research (Publication) Heart Failure Cardiovascular Disease Srivastava Lab Theodoris Lab AI CRISPR/Gene Editing Disease Models Stem Cells/iPSCs