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Scientists used a new method to screen 10,000 combinations of gene edits in immune cells engineered to fight cancer
News Release Research (Publication) Cancer Genomic Immunology Marson Lab CRISPR/Gene Editing
Nob Hill Gazette—Senior Investigator and Nobel Laureate Jennifer Doudna talks about CRISPR, its current and future clinical uses and their ethical implications, her life in science and a new direction for CRISPR called "The Audacious Project".
Gladstone Experts Data Science and Biotechnology Doudna Lab CRISPR/Gene Editing
CVS Health—Innovation in biomedical science is changing the way scientists think about the future of medicine. Gladstone President Deepak Srivastava describes how advances in genomics, gene editing, and cell programming may lead to new cures for human disease.
Gladstone Experts Congenital Heart Disease Cardiovascular Disease Srivastava Lab CRISPR/Gene Editing Human Genetics
Innovative Genomics Institute—Work from Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, and Affiliate Investigator Justin Eyquem demonstrates a new, more efficient and gentle method to introduce CRISPR editing machinery into cells.
Gladstone Experts Genomic Immunology Eyquem Lab Marson Lab CRISPR/Gene Editing
PBS News—Nobel Prize Laureate and Gladstone Senior Investigator Jennifer Doudna reflects on the responsible use of CRISPR, the genome editing tool she co-discovered.
Gladstone Experts Data Science and Biotechnology Doudna Lab CRISPR/Gene Editing
High levels of oxygen can cause lasting health problems in humans. Now scientists know why.
News Release Research (Publication) Cardiovascular Disease Jain Lab CRISPR/Gene Editing
Science is Fun Podcast—Assistant Investigator Seth Shipman describes his remarkable technological advance repurposing CRISPR gene editing technology to record information inside living cells.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
Nature—Alex Marson, MD, PhD, director of the Gladstone-UCSF Institute of Genomic Immunology, and his colleagues have been using CRISPR to increase the therapeutic potential of T cells. This work is part of a worldwide effort to improve the design and manufacturing of cancer-killing ‟CAR-T” cells reviewed in the journal Nature.
Gladstone Experts Cancer Genomic Immunology Marson Lab CRISPR/Gene Editing
Researchers at the Gladstone-UCSF Institute of Genomic Immunology are learning how to harness the power of the human immune system in new ways
Gladstone Experts Cancer Genomic Immunology Carnevale Lab Doudna Lab Marson Lab Pelka Lab Roybal Lab Tang Lab Ye Lab
Nob Hill Gazette—Home to 30 labs and 500 researchers, Gladstone is a hub of cutting-edge research and advances toward cures for the most devastating diseases.
Gladstone Experts Doudna Lab Greene Lab Ott Lab Srivastava Lab Weinberger Lab Yamanaka Lab Big Data CRISPR/Gene Editing Stem Cells/iPSCs
Alex Marson, MD, PhD, director of the Gladstone-UCSF Institute of Genomic Immunology, comments on breakthrough technology developed in his lab that will greatly facilitate the large-scale engineering of immune cells for cell-based therapies.
Gladstone Experts Genomic Immunology Marson Lab CRISPR/Gene Editing
Scientists develop a new approach that produces enough cells for therapeutic applications
News Release Research (Publication) Genomic Immunology Esensten Lab Eyquem Lab Marson Lab CRISPR/Gene Editing
Wired—Measuring which genes are on and which are off in a cell usually requires killing it, meaning any measurement is simply a snapshot in time. Seth Shipman explains how his lab has circumvented this problem by re-engineering parts of a bacterial immune system to create a record of molecular events within a cell.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
Singularity Hub—Genomics tools allow scientists to get a glimpse of what genes are turned on in a cell at one particular moment, but understanding how genes are turned on or off over time, and in what order, has been impossible. Gladstone Investigator Seth Shipman has developed a biological recorder that keeps track of these events, offering a window into how cells change over time.
Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing
Researchers adapt a variation of the CRISPR-Cas9 system to activate genes in human immune cells and study the consequences
News Release Research (Publication) Genomic Immunology Marson Lab CRISPR/Gene Editing
