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Gladstone in the News April 25, 2023

New Approach to CRISPR Delivery Opens the Door to Editing Multiple Genes Safely

Innovative Genomics Institute—Work from Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, and Affiliate Investigator Justin Eyquem demonstrates a new, more efficient and gentle method to introduce CRISPR editing machinery into cells.

Gladstone Experts Genomic Immunology Eyquem Lab Marson Lab CRISPR/Gene Editing

Gladstone in the News April 20, 2023

A Brief but Spectacular Take on the Future of CRISPR

PBS News—Nobel Prize Laureate and Gladstone Senior Investigator Jennifer Doudna reflects on the responsible use of CRISPR, the genome editing tool she co-discovered.

Gladstone Experts Data Science and Biotechnology Doudna Lab CRISPR/Gene Editing

Alan Baik working in the Jain Lab at Gladstone Institutes

Article March 8, 2023

Researchers Discover How Too Much Oxygen Damages Cells and Tissues

High levels of oxygen can cause lasting health problems in humans. Now scientists know why.

News Release Research (Publication) Cardiovascular Disease Jain Lab CRISPR/Gene Editing

Gladstone in the News February 10, 2023

Filming a Movie Using CRISPR Technology

Science is Fun Podcast—Assistant Investigator Seth Shipman describes his remarkable technological advance repurposing CRISPR gene editing technology to record information inside living cells.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

Gladstone in the News January 26, 2023

The Race to Supercharge Cancer-Fighting T Cells

Nature—Alex Marson, MD, PhD, director of the Gladstone-UCSF Institute of Genomic Immunology, and his colleagues have been using CRISPR to increase the therapeutic potential of T cells. This work is part of a worldwide effort to improve the design and manufacturing of cancer-killing ‟CAR-T” cells reviewed in the journal Nature.

Gladstone Experts Cancer Genomic Immunology Marson Lab CRISPR/Gene Editing

Graphic representing research in the Gladstone-UCSF Institute of Genomic Immunology

Article December 7, 2022

Re-Engineering the Human Immune System

Researchers at the Gladstone-UCSF Institute of Genomic Immunology are learning how to harness the power of the human immune system in new ways

Gladstone Experts Cancer Genomic Immunology Carnevale Lab Doudna Lab Marson Lab Pelka Lab Roybal Lab Tang Lab Ye Lab

Gladstone in the News November 3, 2022

Medical Milestones Are Underway at San Francisco’s Gladstone Institutes

Nob Hill Gazette—Home to 30 labs and 500 researchers, Gladstone is a hub of cutting-edge research and advances toward cures for the most devastating diseases.

Gladstone Experts Doudna Lab Greene Lab Ott Lab Srivastava Lab Weinberger Lab Yamanaka Lab Big Data CRISPR/Gene Editing Stem Cells/iPSCs

Gladstone in the News August 29, 2022

A Better, Faster, More Effective Way to Edit Genes

Alex Marson, MD, PhD, director of the Gladstone-UCSF Institute of Genomic Immunology, comments on breakthrough technology developed in his lab that will greatly facilitate the large-scale engineering of immune cells for cell-based therapies.

Gladstone Experts Genomic Immunology Marson Lab CRISPR/Gene Editing

Brian Shy, clinical fellow in the Marson Lab at Gladstone Institutes

Article August 25, 2022

A Cellular Engineering Breakthrough: High-Yield CRISPR Without Viral Vectors

Scientists develop a new approach that produces enough cells for therapeutic applications

News Release Research (Publication) Genomic Immunology Esensten Lab Eyquem Lab Marson Lab CRISPR/Gene Editing

Gladstone in the News August 12, 2022

What If Cells Kept Receipts of Their Gene Expression?

Wired—Measuring which genes are on and which are off in a cell usually requires killing it, meaning any measurement is simply a snapshot in time. Seth Shipman explains how his lab has circumvented this problem by re-engineering parts of a bacterial immune system to create a record of molecular events within a cell.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing

Gladstone in the News August 2, 2022

New DNA ‘Camcorders’ Can Record ‘Movies’ of a Cell’s Development Through Time

Singularity Hub—Genomics tools allow scientists to get a glimpse of what genes are turned on in a cell at one particular moment, but understanding how genes are turned on or off over time, and in what order, has been impossible. Gladstone Investigator Seth Shipman has developed a biological recorder that keeps track of these events, offering a window into how cells change over time.

Gladstone Experts Data Science and Biotechnology Shipman Lab CRISPR/Gene Editing