Gladstone NOW: The Campaign Join Us on the Journey✕
Isha Jain, PhD, and her team developed a drug that mimics the effects of breathing low oxygen, which could be life-saving for people with mitochondrial diseases who rarely survive past childhood. In mice with Leigh Syndrome—the most common childhood mitochondrial disease—the drug extended lifespan three-fold and reversed symptoms, even when given during late stages of disease. The new drug shows the promise of gas-based therapies for mitochondrial diseases and other common brain and cardiovascular conditions for which low oxygen has been shown to be beneficial.
In this video, Jain and research associate Skyler Blume explain the science behind their discovery and the impact it could have for mitochondrial diseases. Read more about this discovery.
Featured Experts
Gladstone NOW: The Campaign
Join Us On The Journey
Science in Seconds | A New Path Toward Life Without Daily HIV Pills
Video
March 20, 2026
Science in Seconds | A New Path Toward Life Without Daily HIV Pills
In this video, Nadia Roan and Ashley George explain how they uncovered a new path toward long-term health without the need for daily HIV pills.
Gladstone Experts Research (Publication) HIV/AIDS Infectious Disease Roan LabWhy Some People Naturally Control HIV Even After Stopping Therapy—and How We Can Leverage That to Treat Others
Article
March 20, 2026
Why Some People Naturally Control HIV Even After Stopping Therapy—and How We Can Leverage That to Treat Others
New research offers a path toward life without daily HIV pills, suggesting common diabetes pill could help achieve long-term remission.
News Release Research (Publication) HIV/AIDS Infectious Disease Roan LabNew Tool Reveals the Secrets of HIV-Infected Cells
Article
March 3, 2026
New Tool Reveals the Secrets of HIV-Infected Cells
Developed by Gladstone scientists, HIV-seq could uncover new opportunities for treating HIV.
News Release Research (Publication) HIV/AIDS Infectious Disease Roan Lab