Join colleagues from Gladstone and Australia’s Murdoch Children’s Research Institute (MCRI) for a day of scientific exchange focused on advancing cardiovascular research.
You’ll hear presentations showcasing innovative discoveries from investigators across both organizations, learn about exciting new approaches to understanding and treating cardiovascular disease, and connect with researchers at every career stage.
Whether you’re looking to expand your scientific perspective, spark new ideas, or build collaborations with colleagues across institutions, this symposium offers an opportunity to engage with a community working toward a common goal: improving cardiovascular health.
This symposium is supported by the American Australian Association.
Agenda
Breakfast
Welcome and Opening Remarks
Enzo Porrello, PhD | MCRI
Christina Theodoris, MD, PhD | Gladstone Institutes
SESSION 1: HEART DEVELOPMENT AND REGENERATION
Transcriptional Regulation of Cardiogenesis
Benoit Bruneau, PhD | Gladstone Institutes
Cellular Reprogramming as a Basis for Heart Disease
Deepak Srivastava, MD | President, Gladstone Institutes
Group and Speaker Photo
Break
SESSION 2: HEART DISEASE
Chromatin Control of Cardiac Inflammation, Disease, and Repair
Michael Alexanian, PhD | Gladstone Institutes
Dissecting the Sex Differences in the Genetic Architecture of Coronary Artery Disease
Catherine Tcheandjieu, DVM, PhD | Gladstone Institutes
Carma: Reporterless, Spatially-Resolved Contractility for 2D Cardiomyocytes
Mark Pocock, PhD | MCRI
SESSION 3: ENABLING TECHNOLOGIES
An Automated Cell Signaling Platform for Next-Generation Drug Screening
Sean Humphrey, PhD | MCRI
Foundational AI Models to Enable Predictions in Network Biology
Christina Theodoris, MD, PhD | Gladstone Institutes
Making the Measurements Routine: Cardiac Analysis Tooling at MCRI
Jerico Revote | MCRI
Lunch
SESSION 4: THERAPEUTIC DEVELOPMENT
Identifying Therapeutic Targets in Cardiomyopathy
David Elliott, PhD | MCRI
Leveraging Human Genetic Variation to Therapeutically Target Hundreds of Genes With Dominant & Dispensable Disease Alleles
Bruce Conklin, MD | Gladstone Institutes
AI-Driven Therapeutic Target Discovery for ALPK3-Related Cardiomyopathy
York Zhang, MS | Gladstone Institutes
SESSION 5: CARDIOVASCULAR GENETICS
Restoration of NRG-ERBB Signaling Rescues Cardiac Function in Genetically Diverse Forms of DCM
Enzo Porrello, PhD | MCRI
A Functional Kinome Screen in iPSC-Derived Cardiomyocytes
Ellen Keen, PhD | MCRI
3D Chromatin Organisation as a Novel Mechanism for Understanding Transcription Factor Haploinsufficiency
Zoe Grant, PhD | Gladstone Institutes
SESSION 6: MCRI BIOBANK
Melbourne Children’s Heart Tissue Bank
Adam Piers, PhD | MCRI
CLOSING
Closing Remarks
Enzo Porrello, PhD | MCRI
Christina Theodoris, MD, PhD | Gladstone Institutes
