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Gladstone scientists uncover novel aspects of HIV infection by monitoring sugars at the surface of individual immune cells
News Release Research (Publication) HIV/AIDS Virology Roan Lab
San Francisco Chronicle—A year has passed since California dropped most public health restrictions related to COVID-19, but the pandemic isn’t over. Senior Investigator Warner Greene notes that the virus is still spreading effectively, and people can be infected repeatedly with different subvariants.
Gladstone Experts COVID-19 Virology Greene Lab
San Francisco Chronicle—A study in the Mission District of San Francisco tracked how COVID-19 symptoms have changed over the course of the pandemic. Gladstone virologist Nadia Roan explains that the Omicron variant infects the upper respiratory tract and triggers a localized immune response, which may in part explain why individuals infected during the Omicron wave were less likely to experience severe illness.
Gladstone Experts COVID-19 Virology Roan Lab
Washington Post—Even as COVID restrictions are easing, case numbers are rising around the country. Melanie Ott, director of the Gladstone Institute of Virology, explains that recent research from her group shows that individuals infected with the Omicron variant have limited natural immunity, and may still be susceptible to infection with Omicron subvariants.
Gladstone Experts COVID-19 Virology Ott Lab
ABC News—Gladstone virologists investigated the effect of the Omicron variant on the immune response. Melanie Ott describes her team’s discovery that previous infection with Omicron does not result in strong immunity to other known SARS-CoV-2 variants. However, as Nadia Roan explains, individuals who were vaccinated before becoming infected with Omicron did have a broadly protective immune response, emphasizing the importance of the vaccines in saving lives.
Gladstone Experts COVID-19 Virology Doudna Lab Greene Lab Ott Lab Roan Lab
USA Today—When the Omicron variant of SARS-CoV-2 swept the country this winter, many had hoped it might help move the population closer to herd immunity. However, Director of the Gladstone Institute of Virology Melanie Ott describes her team’s research that shows that previous infection with Omicron does not provide strong protection against infection with other variants.
Gladstone Experts COVID-19 Virology Ott Lab
Without vaccination, infection with Omicron fails to confer robust immunity against other COVID-19 variants
News Release Research (Publication) COVID-19 Virology Doudna Lab Ott Lab Roan Lab
ABC News—COVID-19 case numbers are rising in the San Francisco Bay Area, driven by sublineages of the Omicron variant. Gladstone virologist Warner Greene explains that the new subvariants are more infectious, and can evade the antibodies produced in response to vaccination and previous infection.
Gladstone Experts COVID-19 Virology Greene Lab
STAT News—COVID-19 case numbers are rising once again across the United States. Melanie Ott, director of the Gladstone Institute of Virology, explains that the virus is adapting to a new immune landscape, with variants emerging that are able to cause infection even in individuals who were previously infected.
Gladstone Experts COVID-19 Virology Ott Lab
New class of resistance-proof drugs could one day transform treatments for viral diseases
News Release Research (Publication) Center for Cell Circuitry Virology Weinberger Lab Chaturvedi
A new platform designed by Gladstone scientists for studying how the immune system responds to hepatitis C virus could speed the hunt for a vaccine
News Release Research (Publication) Hepatitis C Virology McDevitt Lab Ott Lab Organoids
A new catalog to help better understand how HIV hijacks human cells
Research (Publication) HIV/AIDS Data Science and Biotechnology Genomic Immunology Virology Krogan Lab Marson Lab
ABC News—The FDA recently announced that they would authorize a second COVID-19 vaccine booster shot for people 50 and older, and those 12 and older who are immunocompromised. Senior Investigator Warner Greene explains that the second booster can protect people who don’t have vigorous immune systems from infection, and predicts that it may be more broadly recommended for all adults in the months to come.
Gladstone Experts COVID-19 Virology Greene Lab
CBC—The FDA recently authorized a fourth dose of the Pfizer-BioNTech COVID-19 vaccine for all individuals over aged 50, and for those 12 and older with immunodeficiencies. Melanie Ott, director of the Gladstone Institute of Virology, explains that whereas a fourth shot may not be urgently necessary for individuals who are young and healthy, she does encourage those eligible to ensure that they get their third shot (first booster).
Gladstone Experts COVID-19 Virology Ott Lab
ABC News—A sub-variant of Omicron known as BA.2 is causing a spike in COVID-19 cases in Europe, and is predicted to become the globally dominant variant in the coming weeks. However, Senior Investigator Warner Greene says that vaccinated and boosted individuals are still well protected against serious illness, and spread of this new variant is unlikely to lead to new lockdowns.
Gladstone Experts COVID-19 Virology Greene Lab
