Article Type

1 - 5 of 5 Results       Clear All

Using Cancer’s ’Superpower’ to Boost T-cell Therapies in Mice

Gladstone in the News February 12, 2024

Using Cancer’s ’Superpower’ to Boost T-cell Therapies in Mice

Fierce Biotech—A naturally occurring mutation in T cells that leads to lymphoma can be weaponized to make engineered T-cell therapies more effective against cancer, including melanoma, findings from a new study in mice suggest. The study’s co-leads, dermatologist Jaehyuk Choi and scientist Kole Roybal, have launched a new biotech company called Moonlight Bio to take their findings to the clinic.

Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab Genomics

Turbocharged CAR-T Cells Melt Tumours in Mice—Using a Trick from Cancer Cells

Gladstone in the News February 7, 2024

Turbocharged CAR-T Cells Melt Tumours in Mice—Using a Trick from Cancer Cells

Nature—Cancer cells are the ultimate survivors, riddled with mutations that let them thrive when healthy cells would die. These same mutations can boost the ability of game-changing cell therapies to quash cancer, a study in mice shows. “Natural T-cell function isn’t good enough. We need to explore the extremes of T-cell function,” says Kole Roybal, co-author of the new paper.

Research (Publication) Cancer Genomic Immunology Parker Institute for Cancer Immunotherapy Roybal Lab Genomics

More News

Are You a Journalist Looking to Write about Gladstone?

Explore Info for Media