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Isha Jain and Skyler Blume explain the science behind their discovery and the impact it could have for mitochondrial diseases.
Research (Publication) Jain Lab
Science Alert—Gladstone Investigator Isha Jain and her colleagues developed a drug that reduces oxygen delivery from blood to tissues and could help prevent brain damage caused by diseases that cause a toxic oxygen buildup.
Jain Lab Cardiovascular Disease
Gladstone researchers develop a drug that mimics the cellular effects of low-oxygen therapy for the treatment of inherited mitochondrial diseases.
News Release Research (Publication) Jain Lab
Arc Institute—Gladstone investigator Isha Jain joins Arc Institute’s new cohort of core investigators to drive visionary research into complex human disease. She will receive unrestricted funding to advance her research on how the body senses and responds to variations in oxygen levels and vitamins.
Grants Jain Lab
A new study from Gladstone Institutes sheds light on the molecular workings at play when oxygen exceeds normal levels, with findings that may one day inform the decision to use supplemental oxygen as a medical treatment
News Release Research (Publication) Cardiovascular Disease Jain Lab
High levels of oxygen can cause lasting health problems in humans. Now scientists know why.
News Release Research (Publication) Cardiovascular Disease Jain Lab CRISPR/Gene Editing
When mice are exposed to chronically low levels of oxygen, similar to those experienced at 4,500 meters of elevation, their metabolism changes
News Release Research (Publication) Cardiovascular Disease Jain Lab
Graduate Student Will Flanigan shares the importance of LGBTQ+ representation in STEM
Jain Lab Shipman Lab
Funds will support Isha Jain’s innovative disease research with potential for big impact
Grants Cardiovascular Disease Jain Lab
A scientist since childhood, Jain will now lead a lab at Gladstone to study the balance of oxygen levels in the human body
Institutional News News Release Profile Cardiovascular Disease Jain Lab
