A New Therapeutic Window for Patients with Genetic Neuropathy Disorders
A New Therapeutic Window for Patients with Genetic Neuropathy Disorders
An 8-year-old with CMT meets with Gladstone researchers
Gladstone Experts Conklin LabGladstone NOW: The Campaign Join Us on the Journey ✕
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An 8-year-old with CMT meets with Gladstone researchers
Gladstone Experts Conklin LabAlzforum—Loss of synapses in the brain is associated with progression of Alzheimer’s disease. However, a new study led by Lennart Mucke, director of the Gladstone Institute of Neurological Disease, shows that in mice, a mutation associated with increased risk of Alzheimer’s disease results in an excess of synapses. In conjunction with recent work from a few other groups, this suggests that removal of synapses may actually play a protective role against Alzheimer’s, at least early in the disease process.
Gladstone Experts Alzheimer’s Disease Neurological Disease Mucke LabNob Hill Gazette—Senior Investigator and Nobel Laureate Jennifer Doudna talks about CRISPR, its current and future clinical uses and their ethical implications, her life in science and a new direction for CRISPR called “The Audacious Project”.
Gladstone Experts Data Science and Biotechnology Doudna Lab CRISPR/Gene EditingCVS Health—Innovation in biomedical science is changing the way scientists think about the future of medicine. Gladstone President Deepak Srivastava describes how advances in genomics, gene editing, and cell programming may lead to new cures for human disease.
Gladstone Experts Congenital Heart Disease Cardiovascular Disease Srivastava Lab CRISPR/Gene Editing Human GeneticsNature Podcast—Assistant Investigator Christina Theodoris explains how she and her collaborators used artificial intelligence to uncover how genes work together to control cells and tissues, even in situations such as rare diseases where data are in limited supply.
Gladstone Experts Cardiovascular Disease Theodoris Lab AIThe Atlantic—The next generation of COVID vaccines may be directed against just one lineage of the Omicron strain. Melanie Ott, director of the Gladstone Institute of Virology, explains why that could be a smart strategy to elicit a strong immune response.
Gladstone Experts COVID-19 Virology Ott LabSan Francisco Chronicle—Gladstone Senior Investigator Nadia Roan explains that while prior vaccination or exposure to COVID-19 may confer long-term protection against serious disease, a booster shot with the bivalent vaccine will protect you for a few months against new infection.
Gladstone Experts COVID-19 Virology Roan LabNew York Times—A group of studies comparing the human genome to that of 239 other mammalian species has cast light on what makes humans unique. In particular, work from Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, shows that changes to the way DNA folds may have been a part of what allowed humans to evolve large, powerful brains.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics Human GeneticsPopular Science—A new study from Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, indicates that chance structural changes in the human genome were what allowed humans to evolve the larger brains that set us apart from our primate ancestors.
Gladstone Experts Data Science and Biotechnology Pollard Lab Genomics Human GeneticsInnovative Genomics Institute—Work from Alex Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, and Affiliate Investigator Justin Eyquem demonstrates a new, more efficient and gentle method to introduce CRISPR editing machinery into cells.
Gladstone Experts Genomic Immunology Eyquem Lab Marson Lab CRISPR/Gene EditingPBS News—Nobel Prize Laureate and Gladstone Senior Investigator Jennifer Doudna reflects on the responsible use of CRISPR, the genome editing tool she co-discovered.
Gladstone Experts Data Science and Biotechnology Doudna Lab CRISPR/Gene EditingColleagues look back on Warner Greene’s 40 year career
Gladstone Experts History HIV/AIDS Virology Greene LabNational Institutes of Health—Senior Investigator Katie Pollard, PhD, is featured for her work on genome organization during heart development and talks about her career path in a recent highlight of the National Institutes of Health’s 4D Nucleome program.
Gladstone Experts Data Science and Biotechnology Pollard Lab GenomicsThe Wall Street Journal—Induced pluripotent stem cells have the potential to be used in innovative therapies for conditions like for Parkinson’s disease, macular degeneration, and heart failure. Gladstone Senior Investigator Shinya Yamanaka, who was the first to develop the technology, describes how a patient’s own cells can be used to generate tissue for transplantation.
Gladstone Experts Yamanaka Lab Stem Cells/iPSCsGladstone scientists make headway toward new treatments for people with chronic long-term effects
Gladstone Experts Traumatic Brain Injury Neurological Disease Akassoglou Lab Paz Lab Srivastava Lab Deep Dive