Gladstone maintains an active and diverse intellectual property (IP) portfolio around technologies, novel approaches to treating disease, and specific therapies.
Several options for licensing Gladstone IP are available to both new start-ups, established companies, and research institutions.
Contact the Corporate Liaison and Ventures Team for more information on licensing opportunities.
Patents
Additional technologies not listed here may be available for discussion under confidential disclosure agreement. Contact our legal team for licensing inquiries.
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Mouse Model of Chronic Heart Failure and Coronary Atherosclerosis Regression
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Virion-Based Fusion Assay
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Histone Deacetylase and Methods of Use Thereof
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Robotic Microscopy Systems
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Acyl CoA: Cholesterol Acyltransferase (ACAT-2)
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Methods of Detecting Neurological Disorders
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Immunogenic Compositions Comprising HIV-1 Acetylated Tat Polypeptides
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Methods and Compositions for Reducing Amyloid Beta Levels
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Methods for Treating Lentivirus Infections
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Diacylglycerol O-Acyltransferase 2α (DGAT2α)
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Methods of Treating Smooth Muscle Cell Disorders
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Methods and Compositions for the Synergistic Activation of Latent HIV
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Inhibitors of Kynurenine-3-Monooxygenase
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Method of Increasing Cathepsin B-Induced Cleavage of Amyloid-Β Peptides
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Small Molecule Inhibitors of Kynurenine-3-Monooxygenase
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Method for Identifying Agents Capable of Inhibiting APOBEC3C Activity in HIV-Infected Cells
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Methods of Modulating Lipid Concentrations in Eukaryotic Cells
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Use of SIRT1 Activators or Inhibitors to Modulate an Immune Response
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Methods and Compositions for Reducing Amyloid Beta Levels
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Treatment of HIV-1 Infection and AIDS
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Methods of Treating Neurodegenerative Disease
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Compositions and Methods for Treating Neurological Disorders
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Methods for the Reactivation of Latent HIV Using Cytosine Methylation Inhibitors and NF-ΚB Activators
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Methods of Generating Neural Stem Cells
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Compositions and Methods for Regulating Glucose Metabolism
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Methods of Promoting CNS Neuronal Repair by Inhibiting LRP-1
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Methods of Modulating Smooth Muscle Cell Proliferation and Differentiation
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Generating Hepatocytes
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Generating Definitive Endoderm and Pancreatic Progenitor Cells
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Compositions and Methods for Treating Dengue Virus Infection
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Substituted Benzoxazine and Related Compounds
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Dual-Color HIV Reporter System for the Detection of Latently Infected Cells
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Compositions and Methods of Use Thereof for Identifying Anti-Viral Agents
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Compositions, Systems, and Methods for Gene Expression Noise Drug Screening and Uses Thereof
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Automated Robotic Microscopy Systems
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Small Molecule Cellular Reprogramming to Generate Neuronal Cells
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Detection of Genome Editing
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Methods for Inducing Cardiomyogenesis
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In Vitro Methods of Differentiating Stem Cells into Neurons and Neurons Generated Using the Same
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Methods for Treating a Cytomegalovirus Infection
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Methods and Compositions for Producing Pancreatic Beta Cells
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Reversion of Primed Pluripotent Stem Cells to Naive Pluripotent Stem Cells
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Methods for Modulating Genome Editing
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Compositions and Methods for Reactivating Latent Immunodeficiency Virus
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Methods and Compositions for Treating Obesity and/or Diabetes and for Identifying Candidate Treatment Agents
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Generation of Expandable Cardiovascular Progenitor Cells
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Methods of Treating Disease by Metabolic Control of T-Cell Differentiation
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Chemical Reprogramming to Generate Neuronal Cells
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In Vitro Assays for Inhibition of Microglial Activation
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Compositions and Methods for Reactivating Latent Immunodeficiency Virus
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Method of Determining Cellular Protein Homeostasis
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