Gladstone maintains an active and diverse intellectual property (IP) portfolio around technologies, novel approaches to treating disease, and specific therapies.

Several options for licensing Gladstone IP are available to both new start-ups, established companies, and research institutions.

Contact the Corporate Liaison and Ventures Team for more information on licensing opportunities.

Patents

Additional technologies not listed here may be available for discussion under confidential disclosure agreement. Contact our legal team for licensing inquiries.

TITLEPATENT OR PUBLICATION NUMBER
Method of Determining Cellular Protein Homeostasis
Compositions and Methods for Reactivating Latent Immunodeficiency Virus
In Vitro Assays for Inhibition of Microglial Activation
Chemical Reprogramming to Generate Neuronal Cells
Methods of Treating Disease by Metabolic Control of T-Cell Differentiation
Generation of Expandable Cardiovascular Progenitor Cells
Methods and Compositions for Treating Obesity and/or Diabetes and for Identifying Candidate Treatment Agents
Compositions and Methods for Reactivating Latent Immunodeficiency Virus
Methods for Modulating Genome Editing
Reversion of Primed Pluripotent Stem Cells to Naive Pluripotent Stem Cells
Methods and Compositions for Producing Pancreatic Beta Cells
Methods for Treating a Cytomegalovirus Infection
In Vitro Methods of Differentiating Stem Cells into Neurons and Neurons Generated Using the Same
Methods for Inducing Cardiomyogenesis
Detection of Genome Editing
Small Molecule Cellular Reprogramming to Generate Neuronal Cells
Automated Robotic Microscopy Systems
Compositions, Systems, and Methods for Gene Expression Noise Drug Screening and Uses Thereof
Compositions and Methods of Use Thereof for Identifying Anti-Viral Agents
Dual-Color HIV Reporter System for the Detection of Latently Infected Cells
Substituted Benzoxazine and Related Compounds
Compositions and Methods for Treating Dengue Virus Infection
Generating Definitive Endoderm and Pancreatic Progenitor Cells
Generating Hepatocytes
Methods of Modulating Smooth Muscle Cell Proliferation and Differentiation
Methods of Promoting CNS Neuronal Repair by Inhibiting LRP-1
Compositions and Methods for Regulating Glucose Metabolism
Methods of Generating Neural Stem Cells
Methods for the Reactivation of Latent HIV Using Cytosine Methylation Inhibitors and NF-ΚB Activators
Compositions and Methods for Treating Neurological Disorders
Methods of Treating Neurodegenerative Disease
Treatment of HIV-1 Infection and AIDS
Methods and Compositions for Reducing Amyloid Beta Levels
Use of SIRT1 Activators or Inhibitors to Modulate an Immune Response
Methods of Modulating Lipid Concentrations in Eukaryotic Cells
Method for Identifying Agents Capable of Inhibiting APOBEC3C Activity in HIV-Infected Cells
Small Molecule Inhibitors of Kynurenine-3-Monooxygenase
Method of Increasing Cathepsin B-Induced Cleavage of Amyloid-Β Peptides
Inhibitors of Kynurenine-3-Monooxygenase
Methods and Compositions for the Synergistic Activation of Latent HIV
Methods of Treating Smooth Muscle Cell Disorders
Diacylglycerol O-Acyltransferase 2α (DGAT2α)
Methods for Treating Lentivirus Infections
Methods and Compositions for Reducing Amyloid Beta Levels
Immunogenic Compositions Comprising HIV-1 Acetylated Tat Polypeptides
Methods of Detecting Neurological Disorders
Acyl CoA: Cholesterol Acyltransferase (ACAT-2)
Robotic Microscopy Systems
Histone Deacetylase and Methods of Use Thereof
Virion-Based Fusion Assay
Mouse Model of Chronic Heart Failure and Coronary Atherosclerosis Regression