Gladstone in the News
July 25, 2022
The Daily Californian—Senior Investigator Melanie Ott, MD, PhD, and collaborator Abdullah Syed, PhD, a postdoctoral fellow in the laboratory of Senior Investigator Jennifer Doudna, explain how they discovered that antibodies against early versions of the SARS-CoV-2 virus do not protect well against the now widespread and highly contagious Omicron variant, and recommend masking to avoid new infections.
Gladstone Experts
COVID-19
Data Science and Biotechnology
Virology
Doudna Lab
Ott Lab
Gladstone in the News
July 19, 2022
NIH Director’s Blog—Recent work from the team of Gladstone Associate Investigator Nadia Roan, PhD, and their colleagues at The Wistar Institute is featured in this week's NIH Director's Blog. The work uncovers intriguing evidence for the role of sugars at the surface of immune cells in HIV infection.
Gladstone Experts
HIV/AIDS
Virology
Roan Lab
Gladstone in the News
June 30, 2022
ABC7 News—As Omicron BA.4 and BA.5 variants overtake previous coronavirus variants across the United States, Gladstone Associate Investigator Nadia Roan, PhD, explains that their success may owe both to their ability to escape our immune system and to their accelerated replication rate. She suggests that more effort should be made to block infection at the level of the airways, the virus's entry point into our body.
Gladstone Experts
COVID-19
Roan Lab
Gladstone in the News
June 22, 2022
Cancer Research Institute—The Cancer Research Institute recently announced its newest cohort of Scientists Taking Risks (STAR) funding for high risk/high reward research in tumor biology. Of the six recipients, three are core members of the Gladstone-UCSF Institute of Genomic Immunology: Kole Roybal, Ansuman Satpathy, and Matthew Spitzer.
Awards
Gladstone Experts
Genomic Immunology
Gladstone in the News
June 14, 2022
San Francisco Chronicle—A year has passed since California dropped most public health restrictions related to COVID-19, but the pandemic isn’t over. Senior Investigator Warner Greene notes that the virus is still spreading effectively, and people can be infected repeatedly with different subvariants.
Gladstone Experts
COVID-19
Virology
Greene Lab
Gladstone in the News
May 29, 2022
San Francisco Chronicle—A study in the Mission District of San Francisco tracked how COVID-19 symptoms have changed over the course of the pandemic. Gladstone virologist Nadia Roan explains that the Omicron variant infects the upper respiratory tract and triggers a localized immune response, which may in part explain why individuals infected during the Omicron wave were less likely to experience severe illness.
Gladstone Experts
COVID-19
Virology
Roan Lab
Gladstone in the News
May 28, 2022
Washington Post—Even as COVID restrictions are easing, case numbers are rising around the country. Melanie Ott, director of the Gladstone Institute of Virology, explains that recent research from her group shows that individuals infected with the Omicron variant have limited natural immunity, and may still be susceptible to infection with Omicron subvariants.
Gladstone Experts
COVID-19
Virology
Ott Lab
Gladstone in the News
May 20, 2022
ABC News—Gladstone virologists investigated the effect of the Omicron variant on the immune response. Melanie Ott describes her team’s discovery that previous infection with Omicron does not result in strong immunity to other known SARS-CoV-2 variants. However, as Nadia Roan explains, individuals who were vaccinated before becoming infected with Omicron did have a broadly protective immune response, emphasizing the importance of the vaccines in saving lives.
Gladstone Experts
COVID-19
Virology
Doudna Lab
Greene Lab
Ott Lab
Roan Lab
Gladstone in the News
May 18, 2022
UCSF News—Nevan Krogan, PhD, a senior investigator at Gladstone and the director of the Quantitative Biosciences Institute at UC San Francisco, leads a vast, international collaborative effort to find drugs against COVID-19 called the QBI Coronavirus Research Group (QCRG). The group recently received $67.5 million from the National Institutes of Health, the largest such award in UCSF's history, to pursue work on coronaviruses and other viruses with pandemic potential.
Gladstone Experts
COVID-19
Data Science and Biotechnology
Krogan Lab
Gladstone in the News
May 18, 2022
USA Today—When the Omicron variant of SARS-CoV-2 swept the country this winter, many had hoped it might help move the population closer to herd immunity. However, Director of the Gladstone Institute of Virology Melanie Ott describes her team’s research that shows that previous infection with Omicron does not provide strong protection against infection with other variants.
Gladstone Experts
COVID-19
Virology
Ott Lab
Gladstone in the News
May 12, 2022
ABC News—COVID-19 case numbers are rising in the San Francisco Bay Area, driven by sublineages of the Omicron variant. Gladstone virologist Warner Greene explains that the new subvariants are more infectious, and can evade the antibodies produced in response to vaccination and previous infection.
Gladstone Experts
COVID-19
Virology
Greene Lab
Gladstone in the News
May 12, 2022
STAT News—COVID-19 case numbers are rising once again across the United States. Melanie Ott, director of the Gladstone Institute of Virology, explains that the virus is adapting to a new immune landscape, with variants emerging that are able to cause infection even in individuals who were previously infected.
Gladstone Experts
COVID-19
Virology
Ott Lab
Article
April 28, 2022
An in-depth explainer about what happens in the body after vaccination, and how COVID-19 vaccines compare to other vaccines
Gladstone Experts
COVID-19
Deep Dive
Gladstone in the News
April 20, 2022
KCBS News—Although Omicron and related new variants can infect vaccinated people, Senior Investigator Warner Greene says vaccines still protect us well against severe disease, and urges people to get at least one booster shot.
Gladstone Experts
COVID-19
Center for HIV Cure Research
Greene Lab
Gladstone in the News
April 6, 2022
Fierce Biotech—Alexander Marson, director of the Gladstone-UCSF Institute of Genomic Immunology, and his colleagues at UC San Francisco and the Salk Institute for Biological Studies, recently showed that obese mice with atopic dermatitis had an altered immune response that made them refractory to anti-inflammatory treatment. Fierce Biotech discusses the implications of this finding for the development of drugs against inflammation and asthma.
Gladstone Experts
Genomic Immunology
Marson Lab
Disease Models