Article
September 9, 2024
Mucke, director of the Gladstone Institute of Neurological Disease, discusses what's next for Alzheimer’s research, the role of nonprofit research in developing new therapies, and why he's more hopeful than ever for a future where neurodegenerative diseases are fully treatable—and even preventable.
Alzheimer’s Disease
Neurological Disease
Mucke Lab
Aging
Gladstone in the News
June 19, 2024
Washington Post—Gladstone Senior Investigator Yadong Huang offers commentary on a new study examining the protective power of the rare “Christchurch” gene variant against Alzheimer’s. (Subscription required)
Alzheimer’s Disease
Huang Lab
Gladstone in the News
September 8, 2023
Alzforum—Loss of synapses in the brain is associated with progression of Alzheimer’s disease. However, a new study led by Lennart Mucke, director of the Gladstone Institute of Neurological Disease, shows that in mice, a mutation associated with increased risk of Alzheimer’s disease results in an excess of synapses. In conjunction with recent work from a few other groups, this suggests that removal of synapses may actually play a protective role against Alzheimer’s, at least early in the disease process.
Gladstone Experts
Alzheimer’s Disease
Neurological Disease
Mucke Lab