Convergence Seminar
Jeff Nivala, PhD
Jeff Nivala is an Assistant Professor in the Paul G. Allen School of Computer Science and Engineering at the University of Washington and co-director of the Molecular Information Systems Lab. His research lies at the intersection of molecular technology, computer science, and synthetic biology, with a focus on developing tools for molecular data storage, interfaces, genomics, and proteomics.
His group integrates synthetic biology, biophysics, biochemistry, computer science, and engineering to create next-generation molecular technologies. Current research efforts focus on nanopore sensing, single-molecule protein sequencing, CRISPR-Cas systems, wet-lab automation, machine learning for biological systems design, and cyber-biosecurity.
Abstract
A significant portion of the biomolecular world remains “dark,” limiting our ability to fully understand and engineer living systems. Among the most complex and challenging components is the proteome—the vast collection of proteins that serve as the molecular machines and information-processing elements of the cell. In this talk, I will share my journey on the development of nanopore-based protein sequencing over the past decade from early concepts to recent progress. I will discuss my group's efforts to adapt Oxford Nanopore Technologies' platform for 'long-read' protein sequencing, along with the challenges and opportunities that come with this approach.
Details
Audience
Gladstone and UCSFContact(s)
The Convergence Seminar is organized by Gladstone’s Institute for Data Science and Biotechnology. This seminar series brings together scientists from varying disciplines to solve complex scientific questions and accelerate the path to cures.
Diversity, Equity, and Inclusion
At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.
We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.