Lennart Mucke, MD
Lennart Mucke’s lab focuses on how major neurological and psychiatric conditions, such as Alzheimer’s disease and autism spectrum disorders, cause cognitive deficits, behavioral abnormalities, and other disabling symptoms. The group’s ultimate goal is to advance the understanding of devastating brain disorders to a point where transformative treatments can be developed for their prevention, control, and reversal. Mucke’s discoveries regarding the role of tau in the regulation of neuronal activity paved the path toward the development of tau-lowering therapeutics. In addition, Mucke’s investigations of patients with Alzheimer’s and related models shed new light on the intriguing overlap between Alzheimer’s disease and epilepsy.
Gladstone Science Talks allow investigators to share the latest research from their laboratories. These talks are open to the broader Gladstone community.