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August 13, 2014

Reduction of Tau Protein Improves Symptoms in Model of Severe Childhood Epilepsy

SAN FRANCISCO, CA—Researchers at the Gladstone Institutes have shown that reducing brain levels of the protein tau effectively blocks the development of disease in a mouse model of Dravet syndrome, a severe intractable form of childhood epilepsy.

Epilepsy Mucke Lab

Article June 9, 2014

Better Cognition with Gene Variant Carried by 1 in 5

A joint Gladstone-UCSF study reveals a gene linked to longevity also improves learning and memory. This discovery opens a new path for treating Alzheimer's and other aging-related diseases.

Mucke Lab Aging Alzheimer’s Disease

October 20, 2013

Gladstone Scientist to Receive Prestigious Pacesetter Award

SAN FRANCISCO, CA—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, next week will receive the ARCS Foundation’s 2013 Pacesetter Award for his lifelong dedication to overcoming Alzheimer’s disease—and for mentoring students to take a similar approach.

Mucke Lab Neurological Disease Alzheimer’s Disease

May 14, 2013

Gladstone’s Lennart Mucke Wins MetLife Foundation Award

SAN FRANCISCO, CA—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, today received the MetLife Foundation’s 2013 Award for Medical Research in Alzheimer’s Disease at a scientific briefing and awards ceremony in New York.

Alzheimer’s Disease Mucke Lab

March 23, 2013

Gladstone Scientists Discover that DNA Damage Occurs as Part of Normal Brain Activity

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process.

Alzheimer’s Disease Mucke Lab

August 5, 2012

Gladstone Scientists Discover that Epilepsy Drug Reverses Memory Loss in Animal Model of Alzheimer’s Disease

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that an FDA-approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer’s-related impairments in an animal model of the disease.

Alzheimer’s Disease Epilepsy Mucke Lab

Article July 14, 2012

Gladstone’s Lennart Mucke Receives Lifetime Achievement Award from the Alzheimer’s Association

SAN FRANCISCO—July 15, 2012—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, has received the Khalid Iqbal Lifetime Achievement Award for his exceptional contributions to Alzheimer's disease research. The Alzheimer's Association presented the award to Dr.

Awards Alzheimer’s Disease Mucke Lab

Article November 27, 2010

Gene Therapy Prevents Memory Problems in Mice with Alzheimer’s Disease

SAN FRANCISCO, CA—Scientists at the Gladstone Institute of Neurological Disease (GIND) in San Francisco have discovered a new strategy to prevent memory deficits in a mouse model of Alzheimer's disease.

Alzheimer’s Disease Mucke Lab

September 8, 2010

Strategy Discovered to Prevent Alzheimer-associated Traffic Jams in the Brain

SAN FRANCISCO, CA—Amyloid beta (Αβ) proteins, widely thought to cause Alzheimer's disease, block the transport of vital cargoes inside brain cells.

Alzheimer’s Disease Mucke Lab

Article January 6, 2009

A Special Type of Collagen May Help Protect the Brain Against Alzheimer’s Disease

SAN FRANCISCO, CA—Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aβ) proteins, which are widely thought to cause Alzheimer's disease.

Alzheimer’s Disease Mucke Lab

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Reduction of Tau Protein Improves Symptoms in Model of Severe Childhood Epilepsy

Reduction of Tau Protein Improves Symptoms in Model of Severe Childhood Epilepsy

Better Cognition with Gene Variant Carried by 1 in 5

Better Cognition with Gene Variant Carried by 1 in 5

Gladstone Scientist to Receive Prestigious Pacesetter Award

Gladstone Scientist to Receive Prestigious Pacesetter Award

Gladstone’s Lennart Mucke Wins MetLife Foundation Award

Gladstone’s Lennart Mucke Wins MetLife Foundation Award

Gladstone Scientists Discover that DNA Damage Occurs as Part of Normal Brain Activity

Gladstone Scientists Discover that DNA Damage Occurs as Part of Normal Brain Activity

Gladstone Scientists Discover that Epilepsy Drug Reverses Memory Loss in Animal Model of Alzheimer’s Disease

Gladstone Scientists Discover that Epilepsy Drug Reverses Memory Loss in Animal Model of Alzheimer’s Disease

Gladstone’s Lennart Mucke Receives Lifetime Achievement Award from the Alzheimer’s Association

Gladstone’s Lennart Mucke Receives Lifetime Achievement Award from the Alzheimer’s Association

Gene Therapy Prevents Memory Problems in Mice with Alzheimer’s Disease

Gene Therapy Prevents Memory Problems in Mice with Alzheimer’s Disease

Strategy Discovered to Prevent Alzheimer-associated Traffic Jams in the Brain

Strategy Discovered to Prevent Alzheimer-associated Traffic Jams in the Brain

A Special Type of Collagen May Help Protect the Brain Against Alzheimer’s Disease

A Special Type of Collagen May Help Protect the Brain Against Alzheimer’s Disease

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Congrats to Jennifer Doudna, winner of the 2020 Nobel Prize in Chemistry!