News

Gladstone in the News August 29, 2024

Blood Clotting Protein Discovery Upends Conventional COVID-19 Thinking, IDs Potential Therapy

Inside Precision Medicine—A new study by Gladstone Senior Investigators Katerina Akassoglou and Warner Greene shows that fibrin, a blood coagulation protein, drives the cascade of symptoms that are the hallmarks of infection by the SARS-CoV-2 virus.

Gladstone Experts COVID-19 Akassoglou Lab

Gladstone in the News August 28, 2024

Structure Search Suggests Roles for Thousands of Viral Proteins

Chemical & Engineering News—In a new study, scientists in Jennifer Doudna’s lab probe how viruses interfere with host signaling. Postdoctoral Fellow Jason Nomburg explains how they assembled a database of predicted structures of viral proteins, and used it to find the functions of previously mysterious proteins.

Gladstone Experts Infectious Disease Doudna Lab

Gladstone in the News August 27, 2024

San Francisco’s Role in the Mpox Fight

The Voice of San Francisco—Melanie Ott, director of the Gladstone Institute of Virology, answers questions about mpox at a time when many people are wondering about the virus’s ability to become another global pandemic, and also talks about how she and her team are contributing to the fight against it.

Gladstone Experts Infectious Disease Ott Lab

Gladstone in the News August 5, 2024

A Trainee’s Unconventional Path Into Regenerative Medicine

The Stem Cellar—CIRM intern Josh Nelson shares how he went from working as a technical director for various theaters to pursuing a science career, and explains the work he does in Bruce Conklin’s lab at Gladstone.

Gladstone Experts

Gladstone in the News July 19, 2024

San Francisco Scientists Using AI in Hopes to Better Treat Cancer

ABC7 News—Gladstone's president Deepak Srivastava, and Katie Pollard, director of the Gladstone Institute of Data Science and Biotechnology, explain how scientists are using artificial intelligence to pinpoint the best ways to treat cancer.

Gladstone Experts Cancer Data Science and Biotechnology Pollard Lab Srivastava Lab AI

Gladstone in the News July 19, 2024

With COVID Summer Wave Underway, When Should You Get Your Next Vaccine Shot?

San Francisco Chronicle—With the United States now experiencing a typical summer COVID surge, Gladstone Senior Investigator Nadia Roan helps break down how to make a personal decision about when to get your next vaccine.

Gladstone Experts COVID-19 Infectious Disease Roan Lab

Gladstone in the News January 18, 2024

As Prescribed: Researchers Dive Into the Biology of Autism

KCBS Radio—Diagnoses of autism spectrum disorder, or ASD, have been rising over the past decades, with one in 36 children identified with the condition in 2020 compared to one in 150 back in 2000, according to the US Centers for Disease Control and Prevention. Nevan Krogan, PhD, senior investigator at Gladstone Institutes and director of the Quantitative Biosciences Institute at UC San Francisco, shares new research on genetic changes that contribute to ASD.

Gladstone Experts Research (Publication) Neurological Disease Krogan Lab

Gladstone in the News January 18, 2024

Could Long COVID’s Signs of Immune Dysregulation in the Blood Lead to a Diagnostic Test?

STAT—New research has identified proteins present in the blood of people with long COVID that could point the way to a much-needed diagnostic test and possibly to future therapeutic targets. “The dysregulation they observed is a bit complex, as some complement components go up and others go down, but overall the results suggest that complement pathways are abnormal in people with long COVID,” said Gladstone's Nadia Roan, the senior author of a Nature Immunology paper published earlier in January on immune response in long COVID.

Gladstone Experts COVID-19 Roan Lab

Gladstone in the News January 12, 2024

‘Striking’ Study Reveals Immune System Anomalies in People with Long COVID

San Francisco Chronicle—At least 10 percent of those who survive COVID continue to face debilitating symptoms months after the acute infection resolves. New research from the laboratory of Gladstone Senior Investigator Nadia Roan shows that individuals suffering Long Covid have a dysregulated immune response to the virus and evidence of T cell exhaustion, which may be due to the virus persisting within their bodies.

Gladstone Experts COVID-19 Infectious Disease Roan Lab

Gladstone in the News December 11, 2023

How CRISPR Gene Editing Could Help Treat Alzheimer’s

Nature—Recent work by Gladstone Senior Investigator Yadong Huang and his team on the APOE4 Christchurch mutation is featured in a review of the potential for CRISPR to revert mutations that cause Alzheimer's disease.

Gladstone Experts Alzheimer’s Disease Neurological Disease Huang Lab CRISPR/Gene Editing

Article December 11, 2023

Reflections on a Pandemic: 6 Questions with Melanie Ott

Melanie Ott, director of the Gladstone Institute of Virology, reflects on the breakthroughs driven by the COVID-19 pandemic and explains why virologists’ work is never done

Gladstone Experts COVID-19 Infectious Disease Ott Lab

Gladstone in the News December 3, 2023

Genetic Mechanisms Linking Maternal Diabetes and Birth Defects Uncovered

Genetic Engineering & Biotechnology News—In addition to genetic changes, environmental factors are associated with the development of birth defects. A new study led by Deepak Srivastava, president of Gladstone Institutes, reveals how maternal diabetes alters a small subset of cells in the developing heart in a way that can lead to congenital heart defects.

Gladstone Experts Congenital Heart Disease Diabetes Cardiovascular Disease Srivastava Lab Single Cell

Gladstone in the News November 23, 2023

Inside Long COVID’s War on the Body: Researchers Are Trying to Find Out Whether the Virus Has the Potential to Cause Cancer

Fortune—Researchers are investigating the possibility that people who suffer from Long COVID might be at elevated risk of developing cancer. Melanie Ott, director of the Gladstone Institute of Virology, explains that viruses related to SARS-CoV-2 have been shown to inactivate oncosuppressor proteins, which may predispose patients to cancer.

Gladstone Experts Cancer COVID-19 Infectious Disease Ott Lab

Gladstone in the News November 7, 2023

Special Episode: JAHA Distinguished Hearts and Minds Roundtable

AHA with JAHA Podcast—In a roundtable forum, the American Heart Association’s 2023 Distinguished Scientists describe their contributions to stroke and cardiovascular research. Gladstone President Deepak Srivastava discusses the use of human iPS cells in drug discovery and his hopes for the future of science and medicine, including applications of artificial intelligence.

Gladstone Experts Congenital Heart Disease Cardiovascular Disease Srivastava Lab Human Genetics Stem Cells/iPSCs

Gladstone in the News October 3, 2023

New Paper Points the Way to Make CRISPR Safer by Avoiding Chromosome Loss

Innovative Genomics Institute—Gladstone Senior Investigator Jennifer Doudna and Affiliate Investigator Jimmie Ye, along with collaborators at the Parker Institute for Cancer Immunology and Stanford, have discovered a way to increase the safety of CRISPR editing by preventing chromosome loss, a toxic side-effect of the technology in some cells.

Gladstone Experts Cancer Data Science and Biotechnology Parker Institute for Cancer Immunotherapy Doudna Lab Ye Lab CRISPR/Gene Editing