Hosted by the Gladstone Institute of Neurological Disease
Join us for a one-day symposium to explore cutting-edge approaches to understanding and combating Alzheimer’s disease. This event will spotlight innovative strategies to model, decode, and disrupt the multifactorial etiology of this challenging condition.
What to Expect
- Presentations from leading researchers in the field
- Insights into emerging scientific directions and technologies
- Interactive Q&A discussions bridging diverse areas of Alzheimer’s research
- A lunchtime poster session featuring new ideas and ongoing work from fellow researchers
Program
| Introduction and Overview | |
| 9:00 – 9:15am | Lennart Mucke, MD Director, Gladstone Institute of Neurological Disease Professor of Neurology and Neuroscience, University of California San Francisco |
| Presentations | |
| 9:20 – 9:55am | Dynamic Dysregulation of Parvalbumin Cell States Underlies Altered Gamma Oscillations and Brain Hyperexcitability in Alzheimer’s Disease Jorge Palop, PhD Associate Investigator, Gladstone Institute of Neurological Disease Associate Professor of Neurology, University of California San Francisco |
| 10:00 – 10:35am | Title TBD Ed Lein, PhD Senior Investigator, Allen Institute for Brain Science Affiliate Professor, Departments of Neurological Surgery and Laboratory Medicine and Pathology (DLMP), University of Washington |
| 10:35 – 10:45am | Break |
| 10:45 – 11:20am | Study of APOE2's Protective Role in Alzheimer's Disease Yadong Huang, MD, PhD Senior Investigator, Gladstone Institute of Neurological Disease Professor of Neurology and Pathology, University of California San Francisco |
| 11:25am – 12:00pm | Microglia-Based Cell Therapies for the Brain Marius Wernig, MD, PhD Professor, Departments of Pathology and Chemical and Systems Biology, Co-Director, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Visiting Scientist, Gladstone Institute of Cardiovascular Disease |
| 12:00 – 1:30pm | Lunch and Poster Session |
| 1:35 – 2:10pm | Leveraging Single-Cell Biology to Understand the Noncoding Genome in Alzheimer’s Disease Ryan Corces, PhD Assistant Investigator, Gladstone Institute of Neurological Disease Assistant Professor of Neurology, University of California San Francisco |
| 2:15 – 2:50pm | Dissecting Molecular Heterogeneity in Alzheimer’s Disease at the Cell-Type Level Vilas Menon, PhD Assistant Professor, Department of Neurology, Columbia University Irving Medical Center |
| 2:55 – 3:30pm | Statistical Models to Assess Changes in Cell-Type Composition in Single Cell Studies Reuben Thomas, PhD Associate Director, Bioinformatics Core, Gladstone Institute of Data Science and Biotechnology |
| 3:30 – 3:45pm | Break |
| 3:45 – 4:20pm via Zoom |
Using Complex Genetics in Mice to Unlock the Secrets of Cognitive Resilience Catherine Kaczorowski, PhD Elinor Levine Professor of Dementia Research and Professor of Neurology, Deputy Director of Intervention Testing Program, University of Michigan |
| 4:25 – 5:00pm | Tau Lowering Therapeutic Strategies to Prevent and Reverse Alzheimer’s Disease Related Brain Dysfunctions Lennart Mucke, MD Director, Gladstone Institute of Neurological Disease Professor of Neurology and Neuroscience, University of California San Francisco |
| 5:00 – 5:10pm | Closing Remarks by Yadong Huang, MD, PhD Senior Investigator, Gladstone Institute of Neurological Disease Professor of Neurology and Pathology, University of California San Francisco |
This event is supported by NIA Research Program Project Grant P01 AG073082.
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Diversity, Equity, and Inclusion
At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.
We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.