Gladstone Institute of Cardiovascular Disease
Join colleagues from Gladstone and Australia's Murdoch Children's Research Institute (MCRI) for a day of scientific exchange focused on advancing cardiovascular research.
You'll hear presentations showcasing innovative discoveries from investigators across both organizations, learn about exciting new approaches to understanding and treating cardiovascular disease, and connect with researchers at every career stage.
Whether you're looking to expand your scientific perspective, spark new ideas, or build collaborations with colleagues across institutions, this symposium offers an opportunity to engage with a community working toward a common goal: improving cardiovascular health.
This symposium is supported by the American Australian Association.
Program
| 8:30am | Breakfast |
| 9:00am | Welcome and Opening Remarks Enzo Porrello, PhD | MCRI Christina Theodoris, MD, PhD | Gladstone Institutes |
| Session 1: Heart Development and Regeneration | |
| 9:10am | Transcriptional Regulation of Cardiogenesis Benoit Bruneau, PhD | Gladstone Institutes |
| 9:30am | Cellular Reprogramming as a Basis for Heart Disease Deepak Srivastava, MD | President, Gladstone Institutes |
| 9:50am | Group and Speaker Photo |
| 10:00am | Break |
| Session 2: Heart Disease | |
| 10:30am | Chromatin Control of Cardiac Inflammation, Disease, and Repair Michael Alexanian, PhD | Gladstone Institutes |
| 10:50am | Dissecting the Sex Differences in the Genetic Architecture of Coronary Artery Disease Catherine Tcheandjieu, DVM, PhD | Gladstone Institutes |
| 11:10am | Carma: Reporterless, Spatially-Resolved Contractility for 2D Cardiomyocytes Mark Pocock, PhD | MCRI |
| Session 3: Enabling Technologies | |
| 11:30am | An Automated Cell Signaling Platform for Next-Generation Drug Screening Sean Humphrey, PhD | MCRI |
| 11:50am | Foundational AI Models to Enable Predictions in Network Biology Christina Theodoris, MD, PhD | Gladstone Institutes |
| 12:10pm | Making the Measurements Routine: Cardiac Analysis Tooling at MCRI Jerico Revote | MCRI |
| 12:30pm | Lunch |
| Session 4: Therapeutic Development | |
| 1:30pm | Identifying Therapeutic Targets in Cardiomyopathy David Elliott, PhD | MCRI |
| 1:50pm | Leveraging Human Genetic Variation to Therapeutically Target Hundreds of Genes With Dominant & Dispensable Disease Alleles Bruce Conklin, MD | Gladstone Institutes |
| 2:10pm | AI-Driven Therapeutic Target Discovery for ALPK3-Related Cardiomyopathy York Zhang, MS | Gladstone Institutes |
| Session 5: Cardiovascular Genetics | |
| 2:30pm | Restoration of NRG-ERBB Signaling Rescues Cardiac Function in Genetically Diverse Forms of DCM Enzo Porrello, PhD | MCRI |
| 2:50pm | A Functional Kinome Screen in iPSC-Derived Cardiomyocytes Ellen Keen, PhD | MCRI |
| 3:05pm | 3D Chromatin Organisation as a Novel Mechanism for Understanding Transcription Factor Haploinsufficiency Zoe Grant, PhD | Gladstone Institutes |
| Session 6: MCRI Biobank | |
| 3:20pm | Melbourne Children's Heart Tissue Bank Adam Piers, PhD | MCRI |
| Closing | |
| 3:35pm | Closing Remarks Enzo Porrello, PhD | MCRI Christina Theodoris, MD, PhD | Gladstone Institutes |
About Murdoch Children’s Research Institute
Murdoch Children's Research Institute (MCRI) is Australia's largest child health research institute, ranked among the top three globally for research quality and impact. They are committed to transforming child and adolescent health by improving diagnosis, developing early interventions and pioneering new treatments. MCRI is located at The Royal Children’s Hospital and is at the heart of the Melbourne Biomedical Precinct.
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Diversity, Equity, and Inclusion
At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.
We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.