CRISPR Cures for Cancer
Thursday, November 9, 2023

Join us for the first annual CRISPR Cures for Cancer Symposium. During this 1-day symposium, investigators from the CRISPR Cures for Cancer network—a tri-institutional initiative designed to accelerate cell therapy design and development using genomic technologies—will present their latest work. Learn how they apply cutting-edge technologies to the design and development of novel therapeutic approaches for cancer.

This symposium is also a great opportunity to connect with colleagues and spark new collaborations.

This event is open to investigators who are part of the CRISPR Cures for Cancer initiative, their lab members, as well as members from Gladstone Institutes, UC San Francisco, and the Innovative Genomics Institute. 

Program 

9:00am Welcome and Introduction
Alex Marson, MD, PhD, Gladstone Institutes
SESSION 1: TOOLS & TECHNOLOGIES
9:15am Peptide-Mediated CRISPR Delivery for Next-Generation Cell Therapy Engineering
Ross Wilson, PhD, UC Berkeley
9:35am In Vivo Delivery of Gene Editing Enzymes with Lipid Nanoparticles
Niren Murthy, PhD, UC Berkeley
9:55am Improving Cas9 Delivery by Enveloped Delivery Vehicles
Wayne Ngo, PhD, UC Berkeley
10:15am Toward the Clinical Development of Synthetic Immunity to Cancer
Kole Roybal, PhD, UC San Francisco
10:35am Break
SESSION 2: TUMOR IMMUNOLOGY & SCREENING
10:50am High-Throughput Genomics in Cancer Immunotherapy
Ansu Satpathy, MD, PhD, Stanford University
11:10am Building an Organoid Platform to Study Cytokine Signaling in Colon Cancer
Jonathan Braverman, PhD, UC Berkeley
11:30am Decoding and Reprogramming T Cell Circuits with CRISPR
Alex Marson, MD, PhD, Gladstone Institutes
12:00pm Lunch
SESSION 3: PROJECT LIGHTNING TALKS
1:00pm In Vitro and In Silico Variant Functionalization
Jimmie Ye, PhD, UC San Francisco
1:10pm Systematic Design and Development of Engineered Macrophages with Enhanced Anti-tumor Functions
Roarke Kamber, PhD, UC San Francisco
1:20pm Studying Immune Hubs in CRC Organoid-Based Mouse Models
Karin Pelka, PhD, Gladstone Institutes
1:30pm Developing More Potent CAR T Cell Therapies for Multiple Myeloma
Lawrence Fong, MD, UC San Francisco
1:40pm Development of a Novel Regulatory T (Treg) Cellular Therapy to Enable Site-Specific, Delivery Framework for Tissue Modification
Kaustav Das Gupta, PhD, UC San Francisco
1:50pm Delivery Platforms for CRISPR Epigenetic Editors
James Nuñez, PhD, UC Berkeley
2:00pm Leveraging Liquid Lung Cancer-T Cell Assembloid Platforms to Investigate T Cell Immunotherapy
Khang Nguyen, UC San Francisco
2:10pm Epigenetic Engineering Using CRISPRoff as Novel Therapeutics for Glioblastoma
John Liu, MD, PhD, UC San Francisco
2:20pm Establishing a CRISPR Integration Platform for Clinical Manufacture of Next-Gen Anti-cancer T Cells with Complex Circuits
Ricardo Almeida, PhD, UC San Francisco
2:30pm Break
SESSION 4: TOWARD THE CLINIC
3:00pm Advancing CAR T Cell Therapy Using Ex Vivo and In Vivo CRISPR Editing
Justin Eyquem, PhD, UC San Francisco
3:20pm Unlocking the Full Potential of Immune Cell Therapies with CRISPR Screening Approaches
Julia Carnevale, MD, UC San Francisco
3:40pm Developing CRISPR Engineered Therapies in the Academic Setting
Brian Shy, MD, PhD, UC San Francisco
4:00pm Translating CAR-Ts for Blood Cancers to the Clinic with CRISPR
Arun Wiita, MD, PhD, UC San Francisco
4:20pm Translating CRISPR Cures into the Clinic
Alan Ashworth, PhD, FRS, UC San Francisco
4:50pm Closing
Alan Ashworth, PhD, FRS, UC San Francisco
5:00pm Reception

 

CRISPR Cures for Cancer is a tri-institutional initiative designed to accelerate cell therapy design and development using genomic technologies. CRISPR Cures for Cancer unites researchers at UC San Francisco, Gladstone Institutes, and the Innovative Genomics Institute at UC Berkeley to accelerate the development of novel therapies for a wide variety of cancers by combining genetic discovery and design with innovations in CRISPR technology.
 

Details

Dates
November 9, 2023
Time
9:00am-5:00pm PST
Location
Mahley Auditorium
Audience
Gladstone and UCSF, Scientific
Contact(s)







Diversity, Equity, and Inclusion

At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.

We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.