Infectious Diseases and Human Health Seminar
Monday, December 11, 2023

Ya-Chi Ho, PhD

Associate Professor of Microbial Pathogenesis and Medicine (Infectious Diseases)

Dr. Ho identifies mechanisms of HIV persistence, characterizes HIV-induced immune dysfunction, and develops HIV cure strategies. She identified the first HIV proviral landscape (Cell 2013) and how the immune selection pressure shapes the intact and defective HIV-infected cells (Cell Host & Microbe 2017). She identified HIV-to-host RNA splicing and HIV-driven aberrant cancer gene expression as a mechanism of the clonal expansion of HIV-infected cells (Science Translational Medicine 2020, JCI 2020). She explores CRISPR screen (JVI 2022), 3D chromatin interactions (Genome Research 2023), and single-cell multiomic approaches (Immunity 2022, Immunity 2023) and identifies HIV-host interactions at the chromatin, RNA, and cellular, and systemic levels. She is a Plenary Speaker of AIDS 2023 and was elected a member of The American Society for Clinical Investigation in 2023.

Details

Dates
December 11, 2023
Time
11:00am-12:00pm PST
Location
264 A/B & Online
Audience
Gladstone and UCSF
Contact(s)





Infectious Diseases and Human Health Seminar is a collaborative series hosted by the Gladstone Institute of Virology and Immunology, BioFulcrum, Quantitative Biosciences Institute, and the Host Pathogen Map Initiative at UC San Francisco.

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