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Gladstone Scientists: “ApoE Is an Ideal Target for Halting Progression of Alzheimer’s Disease”

December 4, 2012

Gladstone Scientists: “ApoE Is an Ideal Target for Halting Progression of Alzheimer’s Disease”

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes are recommending a shift in efforts to treat Alzheimer’s disease by developing drugs that target the apoE4 protein, which has long been associated with an increased risk for the disease.

Alzheimer’s Disease Huang Lab Mahley Lab

Gladstone Scientists Discover that Epilepsy Drug Reverses Memory Loss in Animal Model of Alzheimer’s Disease 

August 5, 2012

Gladstone Scientists Discover that Epilepsy Drug Reverses Memory Loss in Animal Model of Alzheimer’s Disease 

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that an FDA-approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer’s-related impairments in an animal model of the disease.

Alzheimer’s Disease Epilepsy Mucke Lab

Gladstone’s Lennart Mucke Receives Lifetime Achievement Award from the Alzheimer’s Association

Article July 14, 2012

Gladstone’s Lennart Mucke Receives Lifetime Achievement Award from the Alzheimer’s Association

SAN FRANCISCO—July 15, 2012—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, has received the Khalid Iqbal Lifetime Achievement Award for his exceptional contributions to Alzheimer’s disease research. The Alzheimer’s Association presented the award to Dr.

Awards Alzheimer’s Disease Mucke Lab

Gladstone Scientists Identify Key Network Mechanism That Could Contribute to Cognitive Problems in Alzheimer’s Disease

Article April 25, 2012

Gladstone Scientists Identify Key Network Mechanism That Could Contribute to Cognitive Problems in Alzheimer’s Disease

SAN FRANCISCO, CA—April 26, 2012—Scientists at the Gladstone Institutes have unraveled a process by which depletion of a specific protein in the brain contributes to the memory problems associated with Alzheimer’s disease.

Alzheimer’s Disease

Gladstone Scientists Find Increased ApoE Protein Levels May Promote Alzheimer’s Disease

Article April 2, 2012

Gladstone Scientists Find Increased ApoE Protein Levels May Promote Alzheimer’s Disease

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have enhanced our understanding of how a protein linked to Alzheimer’s disease keeps young brains healthy, but can damage them later in life—suggesting new research avenues for treating this devastating disease.

Alzheimer’s Disease

Gladstone Scientists Identify Strategies To Protect New Brain Cells Against Alzheimer’s Disease

Article December 2, 2009

Gladstone Scientists Identify Strategies To Protect New Brain Cells Against Alzheimer’s Disease

SAN FRANCISCO, CA—Stimulating the growth of new neurons to replace those lost in Alzheimer’s disease (AD) is an intriguing therapeutic possibility. But will the factors that cause AD allow the new neurons to thrive and function normally?

Alzheimer’s Disease Gan Lab Huang Lab

A Special Type of Collagen May Help Protect the Brain Against Alzheimer’s Disease

Article January 6, 2009

A Special Type of Collagen May Help Protect the Brain Against Alzheimer’s Disease

SAN FRANCISCO, CA—Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aβ) proteins, which are widely thought to cause Alzheimer’s disease.

Alzheimer’s Disease Mucke Lab

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