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The initiative will fast-track new approaches to treat Alzheimer’s disease.
News Release Alzheimer’s Disease
Li Gan, PhD, has been selected to present the Inge Grundke-Iqbal Lecture for Alzheimer’s Research at the Alzheimer’s Association International Conference (AAIC) in Washington, D.C. in July.
Alzheimer’s Disease
Raising levels of the life-extending protein klotho can protect against learning and memory deficits in a mouse model of Alzheimer’s disease, despite the accumulation of Alzheimer-related toxins in the brain.
Mucke Lab Aging Alzheimer’s Disease
Low levels of the naturally occurring protein progranulin exacerbate cellular and cognitive dysfunction, while raising levels can prevent abnormalities in an Alzheimer model.
Alzheimer’s Disease
SAN FRANCISCO, CA—A new study from the Gladstone Institutes has revealed a way to alleviate the learning and memory deficits caused by apoE4, the most important genetic risk factor for Alzheimer’s disease, improving cognition to normal levels in aged mice.
Huang Lab Alzheimer’s Disease
A joint Gladstone-UCSF study reveals a gene linked to longevity also improves learning and memory. This discovery opens a new path for treating Alzheimer's and other aging-related diseases.
Research (Publication) Alzheimer’s Disease Mucke Lab Aging
SAN FRANCISCO, CA—Alzheimer’s disease is one of the greatest challenges facing modern medicine, but there is new hope in the fight against this deadly disease.
Huang Lab Mahley Lab Neurological Disease Alzheimer’s Disease
SAN FRANCISCO, CA—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, next week will receive the ARCS Foundation’s 2013 Pacesetter Award for his lifelong dedication to overcoming Alzheimer’s disease—and for mentoring students to take a similar approach.
Mucke Lab Neurological Disease Alzheimer’s Disease
SAN FRANCISCO, CA—There is no easy way to study diseases of the brain. Extracting brain cells, or neurons, from a living patient is difficult and risky, while examining a patient’s brain post-mortem usually only reveals the disease’s final stages.
Huang Lab Alzheimer’s Disease Stem Cells/iPSCs
SAN FRANCISCO, CA—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, today received the MetLife Foundation’s 2013 Award for Medical Research in Alzheimer’s Disease at a scientific briefing and awards ceremony in New York.
Alzheimer’s Disease Mucke Lab
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process.
Alzheimer’s Disease Mucke Lab
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes are recommending a shift in efforts to treat Alzheimer’s disease by developing drugs that target the apoE4 protein, which has long been associated with an increased risk for the disease.
Alzheimer’s Disease Huang Lab Mahley Lab
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that an FDA-approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer’s-related impairments in an animal model of the disease.
Alzheimer’s Disease Epilepsy Mucke Lab
SAN FRANCISCO—July 15, 2012—Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, has received the Khalid Iqbal Lifetime Achievement Award for his exceptional contributions to Alzheimer's disease research. The Alzheimer's Association presented the award to Dr.
Awards Alzheimer’s Disease Mucke Lab
SAN FRANCISCO, CA—April 26, 2012—Scientists at the Gladstone Institutes have unraveled a process by which depletion of a specific protein in the brain contributes to the memory problems associated with Alzheimer's disease.
Alzheimer’s Disease
